Long-term depression: multiple forms and implications for brain function

PV Massey, ZI Bashir - Trends in neurosciences, 2007 - cell.com
Long-term potentiation (LTP) and long-term depression (LTD) remain widely accepted
vertebrate models for the cellular and molecular mechanisms that underlie synaptic changes …

Long-term depression: a cascade of induction and expression mechanisms

N Kemp, ZI Bashir - Progress in neurobiology, 2001 - Elsevier
The aims of this paper are to provide a comprehensive and up to date review of the mechanisms
of induction and expression of long-term depression (LTD) of synaptic transmission. …

Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression

…, E Molnar, GL Collingridge, ZI Bashir - Journal of …, 2004 - Soc Neuroscience
It is widely believed that long-term depression (LTD) and its counterpart, long-term potentiation
(LTP), involve mechanisms that are crucial for learning and memory. However, LTD is …

Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors

ZI Bashir, ZA Bortolotto, CH Davies, N Berretta… - Nature, 1993 - nature.com
UNDERSTANDING the mechanisms of long-term potentiation (LTP) should provide insights
into the molecular basis of learning and memory in vertebrates. lonotropic glutamate …

Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1

F Conquet, ZI Bashir, CH Davies, H Daniel, F Ferraguti… - Nature, 1994 - nature.com
Metabotropic glutamate receptor 1 (mGluRl) is a member of a large family of G-protein-coupled
glutamate receptors, the physiological functions of which are largely unknown. Mice …

Long-term potentiation of NMDA receptor-mediated synaptic transmission in the hippocampus

ZI Bashir, S Alford, SN Davies, AD Randall… - Nature, 1991 - nature.com
NEUROTRANSMISSION at most excitatory synapses in the brain operates through two types
of glutamate receptor termed α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMP A) …

Differential roles of NR2A and NR2B-containing NMDA receptors in LTP and LTD in the CA1 region of two-week old rat hippocampus

…, PV Massey, ZA Bortolotto, SM Fitzjohn, ZI Bashir… - …, 2007 - Elsevier
The role of NMDA receptors in the induction of long-term potentiation (LTP) and long-term
depression (LTD) is well established but which particular NR2 subunits are involved in these …

[HTML][HTML] Cholinergic neurotransmission is essential for perirhinal cortical plasticity and recognition memory

…, G Duguid, GRI Barker, JP Aggleton, ZI Bashir… - Neuron, 2003 - cell.com
We establish the importance of cholinergic neurotransmission to both recognition memory
and plasticity within the perirhinal cortex of the temporal lobe. The muscarinic receptor …

Different forms of LTD in the CA1 region of the hippocampus: role of age and stimulus protocol

…, J McQueen, S Faulkes, ZI Bashir - European Journal of …, 2000 - Wiley Online Library
In this study, we have investigated the developmental range over which different stimulus
protocols induce long‐term depression (LTD). Low‐frequency stimulation (LFS; 900 stimuli, 1 …

[HTML][HTML] Expression of long-term depression underlies visual recognition memory

…, J Uney, MW Brown, EC Warburton, ZI Bashir - Neuron, 2008 - cell.com
The modifications occurring in the brain during learning and memory are still poorly understood
but may involve long-lasting changes in synaptic transmission (synaptic plasticity). In …