User profiles for Yuyu Song
Yuyu SongHarvard Medical School Verified email at hms.harvard.edu Cited by 4138 |
Axonal transport defects in neurodegenerative diseases
Adult-onset neurodegenerative diseases (AONDs) comprise a heterogeneous group of
neurological disorders characterized by a progressive, age-dependent decline in neuronal …
neurological disorders characterized by a progressive, age-dependent decline in neuronal …
Post-translational modifications of tubulin: pathways to functional diversity of microtubules
Tubulin and microtubules are subject to a remarkable number of post-translational
modifications. Understanding the roles these modifications play in determining the functions and …
modifications. Understanding the roles these modifications play in determining the functions and …
Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS
Many mutations confer one or more toxic function(s) on copper/zinc superoxide dismutase 1
(SOD1) that impair motor neuron viability and cause familial amyotrophic lateral sclerosis (…
(SOD1) that impair motor neuron viability and cause familial amyotrophic lateral sclerosis (…
Optical magnetic detection of single-neuron action potentials using quantum defects in diamond
Magnetic fields from neuronal action potentials (APs) pass largely unperturbed through
biological tissue, allowing magnetic measurements of AP dynamics to be performed …
biological tissue, allowing magnetic measurements of AP dynamics to be performed …
Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases
Aggregated filamentous forms of hyperphosphorylated tau (a microtubule-associated protein)
represent pathological hallmarks of Alzheimer's disease (AD) and other tauopathies. While …
represent pathological hallmarks of Alzheimer's disease (AD) and other tauopathies. While …
Analysis and review of state-of-the-art automatic parking assist system
Y Song, C Liao - … on Vehicular Electronics and Safety (ICVES), 2016 - ieeexplore.ieee.org
The emerging advanced technology, automatic parking assist, makes it possible to free drivers'
hands from bored parking maneuvers and offers the possibility of reducing driver stress. …
hands from bored parking maneuvers and offers the possibility of reducing driver stress. …
[PDF][PDF] Transglutaminase and polyamination of tubulin: posttranslational modification for stabilizing axonal microtubules
Y Song, LL Kirkpatrick, AB Schilling, DL Helseth… - Neuron, 2013 - cell.com
Neuronal microtubules support intracellular transport, facilitate axon growth, and form a basis
for neuronal morphology. While microtubules in nonneuronal cells are depolymerized by …
for neuronal morphology. While microtubules in nonneuronal cells are depolymerized by …
[HTML][HTML] Structure, folding and stability of nucleoside diphosphate kinases
Nucleoside diphosphate kinases (NDPK) are oligomeric proteins involved in the synthesis
of nucleoside triphosphates. Their tridimensional structure has been solved by X-ray …
of nucleoside triphosphates. Their tridimensional structure has been solved by X-ray …
An inherited TUBB2B mutation alters a kinesin-binding site and causes polymicrogyria, CFEOM and axon dysinnervation
…, MA Tischfield, M Peeva, Y Song… - Human molecular …, 2012 - academic.oup.com
Microtubules are essential components of axon guidance machinery. Among β-tubulin
mutations, only those in TUBB3 have been shown to cause primary errors in axon guidance. All …
mutations, only those in TUBB3 have been shown to cause primary errors in axon guidance. All …
[HTML][HTML] Inhibition of fast axonal transport by pathogenic SOD1 involves activation of p38 MAP kinase
Dying-back degeneration of motor neuron axons represents an established feature of
familial amyotrophic lateral sclerosis (FALS) associated with superoxide dismutase 1 (SOD1) …
familial amyotrophic lateral sclerosis (FALS) associated with superoxide dismutase 1 (SOD1) …