The anatomy of the mammalian visual system, from the retina to the neocortex, is organized
hierarchically 1 . However, direct observation of cellular-level functional interactions across …

Biological protein pores and pore-forming peptides can generate a pathway for the flux of
ions and other charged or polar molecules across cellular membranes. In nature, these …

Structural rules underlying functional properties of cortical circuits are poorly understood. To
explore these rules systematically, we integrated information from extensive literature …

Synchronization over networks depends strongly on the structure of the coupling between
the oscillators. When the coupling presents certain regularities, the dynamics can be coarse-…

The mammalian visual system, from retina to neocortex, has been extensively studied at
both anatomical and functional levels. Anatomy indicates the cortico-thalamic system is …

Despite advances in experimental techniques and accumulation of large datasets concerning
the composition and properties of the cortex, quantitative modeling of cortical circuits …

Experimental studies in neuroscience are producing data at a rapidly increasing rate, providing
exciting opportunities and formidable challenges to existing theoretical and modeling …

There is a significant interest in the neuroscience community in the development of large-scale
network models that would integrate diverse sets of experimental data to help elucidate …

Scientists have long conjectured that the neocortex learns the structure of the environment
in a predictive, hierarchical manner. To do so, expected, predictable features are …

Increasing availability of comprehensive experimental datasets and of high-performance
computing resources are driving rapid growth in scale, complexity, and biological realism of …