User profiles for Wolfgang Löscher

Wolfgang Löscher

University of Veterinary Medicine Hannover
Verified email at tiho-hannover.de
Cited by 61317

[BOOK][B] Pharmakotherapie bei Haus-und Nutztieren

W Löscher, FR Ungemach, R Kroker - 2006 - books.google.com
Geschützte Warennamen (Warenzeichen®) werden nicht immer besonders kenntlich gemacht.
Aus dem Fehlen eines solchen Hinweises kann also nicht geschlossen werden, dass es …

The neurobiology of antiepileptic drugs

MA Rogawski, W Löscher - Nature reviews neuroscience, 2004 - nature.com
Antiepileptic drugs (AEDs) provide satisfactory control of seizures for most patients with
epilepsy. The drugs have the remarkable ability to protect against seizures while permitting …

Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations

W Löscher, D Schmidt - Epilepsy research, 1988 - Elsevier
It has been estimated that about 20% of patients with epilepsy cannot be treated successfully
with current antiepileptic drugs14”. It should be emphasized, however, that this global …

Blood-brain barrier active efflux transporters: ATP-binding cassette gene family

W Löscher, H Potschka - NeuroRx, 2005 - Elsevier
The blood-brain barrier (BBB) contributes to brain homeostasis by protecting the brain from
potentially harmful endogenous and exogenous substances. BBB active drug efflux …

Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases

W Löscher, H Potschka - Progress in neurobiology, 2005 - Elsevier
The blood–brain barrier (BBB) serves as a protective mechanism for the brain by preventing
entry of potentially harmful substances from free access to the central nervous system (CNS)…

Animal models of epilepsy for the development of antiepileptogenic and disease-modifying drugs. A comparison of the pharmacology of kindling and post-status …

W Löscher - Epilepsy research, 2002 - Elsevier
Control of epilepsy has primarily focused on suppressing seizure activity by antiepileptic
drugs (AEDs) after epilepsy has developed. AEDs have greatly improved the lives of people …

[BOOK][B] Pharmakotherapie bei Haus-und Nutztieren: Begründet von W. Löscher, FR Ungemach und R. Kroker

W Löscher, A Richter, H Potschka - 2014 - books.google.com
… Der unerwartete Tod von Fritz Rupert Ungemach (2009) und Reinhard Kroker (2012), die
zusammen mit Wolfgang Löscher die ersten 8 Auflagen des Buches verfasst hatten, und ohne …

Drug resistance in brain diseases and the role of drug efflux transporters

W Löscher, H Potschka - Nature Reviews Neuroscience, 2005 - nature.com
Resistance to drug treatment is an important hurdle in the therapy of many brain disorders,
including brain cancer, epilepsy, schizophrenia, depression and infection of the brain with HIV…

The blood-brain barrier and cancer: transporters, treatment, and Trojan horses

JF Deeken, W Löscher - Clinical cancer research, 2007 - AACR
Despite scientific advances in understanding the causes and treatment of human malignancy,
a persistent challenge facing basic and clinical investigators is how to adequately treat …

Role of multidrug transporters in pharmacoresistance to antiepileptic drugs

W Löscher, H Potschka - Journal of pharmacology and experimental …, 2002 - ASPET
Epilepsy, one of the most common neurologic disorders, is a major public health issue. Despite
more than 20 approved antiepileptic drugs (AEDs), about 30% of patients are refractory …