New approaches, techniques and tools invented over the last decade and a half have
revolutionized the functional dissection of neural circuitry underlying Drosophila learning. The new …

In C. elegans, four asymmetric divisions, beginning with the zygote (P0), generate
transcriptionally repressed germline blastomeres (P1–P4) and somatic sisters that become …

MicroRNAs have been associated with many different biological functions, but little is known
about their roles in conditioned behavior. We demonstrate that Drosophila miR-980 is a …

The oocytes of most sexually reproducing animals arrest in meiotic prophase I. Oocyte
growth, which occurs during this period of arrest, enables oocytes to acquire the cytoplasmic …

microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression post-transcriptionally.
Prior studies have shown that they regulate numerous physiological processes …

Specification of primordial germ cells requires global repression of transcription. In C. elegans,
primordial germ cells are generated through four rounds of asymmetric divisions, starting …

In Caenorhabditis elegans, the MEI-1–katanin microtubule-severing complex is required for
meiosis, but must be down-regulated during the transition to embryogenesis to prevent …

In C. elegans embryos, transcriptional repression in germline blastomeres requires PIE-1
protein. Germline blastomere-specific localization of PIE-1 depends, in part, upon regulated …

The restricted spatiotemporal translation of maternal mRNAs, which is crucial for correct cell
fate specification in early C. elegans embryos, is regulated primarily through the 3′UTR. …

Highlights • RISC is required for activity-dependent and sensory-specific protein translation.
• RISC and associated proteins are required for olfactory long-term habituation. • MiR-276a …