Osteoarthritis (OA) is a chronic joint disease characterized by cartilage destruction,
subchondral bone sclerosis, and osteophyte formation. Subchondral bone stiffness has been …

Objective It has been suggested that subchondral bone remodeling plays a role in the
progression of osteoarthritis (OA). To test this hypothesis, we characterized the changes in the rat …

Osteoarthritis is considered as a chronic disease of the whole joint, including articular
cartilage, meniscus, ligament, and peri-articular muscle that may result from multiple …

We characterized the temporal changes in chondrogenic genes and developed a staging
scheme for in vitro chondrogenic differentiation of human mesenchymal stem cells (hMSCs) in …

The use of small antimicrobial peptides or bacteriocins, like nisin, to treat cancer is a new
approach that holds great promise. Nisin exemplifies this new approach because it has been …

Introduction The prevalence of hypovitaminosis D in patients with acute hip fracture was
examined in a population on Sado Island in Japan. There were 85 cases of hip fracture among …

OBJECTIVE: Chondromodulin-I (ChM-I), a cartilage derived anti-angiogenic factor, has
been shown to regulate the vascular invasion during endochondral bone formation. We …

OBJECTIVE: To investigate the disease modifying effects of cathepsin K (CatK) inhibitor L-006235
compared to alendronate (ALN) in two preclinical models of osteoarthritis (OA). …

We present a case of a 32‐year‐old diabetic woman with Prader–Willi syndrome who developed
severe ketoacidosis caused by a sodium‐glucose cotransporter 2 ( SGLT 2) inhibitor, a …

… Toshio Hayami and Shigeyoshi Owa … The following two lemmas can be found in the paper
by Hayami and Owa [3]. … Also, this shows us that we don’t need to consider the case 0 ≦ μ ≦ …