Regulation of lymphokine production and human T lymphocyte activation by 1, 25-dihydroxyvitamin D3. Specific inhibition at the level of messenger RNA.

WF Rigby, S Denome, MW Fanger - The Journal of clinical …, 1987 - Am Soc Clin Investig
The steroid hormone, 1 alpha,25-dihydroxyvitamin D3 (calcitriol), has been shown to inhibit
T cell proliferation, primarily through inhibition of interleukin 2 (IL-2) production. In these …

Escherichia coli Mutants Lacking All Possible Combinations of Eight Penicillin Binding Proteins: Viability, Characteristics, and Implications for Peptidoglycan …

SA Denome, PK Elf, TA Henderson… - Journal of …, 1999 - Am Soc Microbiol
The penicillin binding proteins (PBPs) synthesize and remodel peptidoglycan, the structural
component of the bacterial cell wall. Much is known about the biochemistry of these proteins, …

Characterization of the desulfurization genes from Rhodococcus sp. strain IGTS8

SA Denome, C Oldfield, LJ Nash… - Journal of …, 1994 - Am Soc Microbiol
Rhodococcus sp. strain IGTS8 possesses an enzymatic pathway that can remove covalently
bound sulfur from dibenzothiophene (DBT) without breaking carbon-carbon bonds. The …

Molecular Cloning of Genes Under Control of the Circadian Clock in Neurospora

JJ Loros, SA Denome, JC Dunlap - Science, 1989 - science.org
To investigate the regulation of messenger RNA abundance by circadian clocks, genomic
and complementary DNA libraries were screened with complementary DNA probes enriched, …

Identification and Cloning of Genes Involved in Specific Desulfurization of Dibenzothiophene by Rhodococcus sp. Strain IGTS8

SA Denome, ES Olson, KD Young - Applied and environmental …, 1993 - Am Soc Microbiol
The gram-positive bacterium Rhodococcus sp. strain IGTS8 is able to remove sulfur from
certain aromatic compounds without breaking carbon-carbon bonds. In particular, sulfur is …

Molecular analysis of cDNA clones and the corresponding genomic coding sequences of the Drosophila dunce+ gene, the structural gene for cAMP …

CN Chen, S Denome, RL Davis - Proceedings of the …, 1986 - National Acad Sciences
We have isolated and sequenced cDNA clones representing portions of the polyadenylylated
transcripts of the dunce+ gene. These define an open reading frame of 1086 bases and …

AmpC and AmpH, proteins related to the class C beta-lactamases, bind penicillin and contribute to the normal morphology of Escherichia coli

TA Henderson, KD Young, SA Denome… - Journal of …, 1997 - Am Soc Microbiol
Two proteins that bind penicillin were observed in Escherichia coli infected with lambda
phages 141, 142, 650, and 651 from the Kohara genomic library. These phages carry …

CACNA1B mutation is linked to unique myoclonus-dystonia syndrome

…, DS Verbeek, P Nürnberg, S Denome… - Human molecular …, 2015 - academic.oup.com
Using exome sequencing and linkage analysis in a three-generation family with a unique
dominant myoclonus-dystonia-like syndrome with cardiac arrhythmias, we identified a …

Opioid inhibition of N-type Ca2+ channels and spinal analgesia couple to alternative splicing

A Andrade, S Denome, YQ Jiang… - Nature …, 2010 - nature.com
Alternative pre-mRNA splicing occurs extensively in the nervous systems of complex
organisms, including humans, considerably expanding the potential size of the proteome. Cell-…

Differential ubiquitination and proteasome regulation of CaV2. 2 N-type channel splice isoforms

…, A Andrade, TD Helton, S Denome… - Journal of …, 2012 - Soc Neuroscience
Ca V 2.2 (N-type) calcium channels control the entry of calcium into neurons to regulate
essential functions but most notably presynaptic transmitter release. Ca V 2.2 channel …