User profiles for Sumantra Chattarji
Sumantra ChattarjiNational Centre for Biological Sciences, TIFR Verified email at ncbs.res.in Cited by 15323 |
Stress, memory and the amygdala
B Roozendaal, BS McEwen, S Chattarji - Nature Reviews …, 2009 - nature.com
Emotionally significant experiences tend to be well remembered, and the amygdala has a
pivotal role in this process. But the efficient encoding of emotional memories can become …
pivotal role in this process. But the efficient encoding of emotional memories can become …
[PDF][PDF] Correction of fragile X syndrome in mice
Fragile X syndrome (FXS) is the most common form of heritable mental retardation and the
leading identified cause of autism. FXS is caused by transcriptional silencing of the FMR1 …
leading identified cause of autism. FXS is caused by transcriptional silencing of the FMR1 …
Effects of chronic stress on dendritic arborization in the central and extended amygdala
A differential role has been suggested for two important areas in the neural circuitry of stress,
central nucleus of the amygdala (CeA) and bed nucleus of stria terminalis (BNST) in the …
central nucleus of the amygdala (CeA) and bed nucleus of stria terminalis (BNST) in the …
Chronic stress induces contrasting patterns of dendritic remodeling in hippocampal and amygdaloid neurons
The hippocampus and the amygdala are essential components of the neural circuitry mediating
stress responses. The hippocampus, which provides negative feedback regulation of the …
stress responses. The hippocampus, which provides negative feedback regulation of the …
[PDF][PDF] Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration
…, S Malkani, D Zhang, BSS Rao, S Chattarji… - Neuron, 2004 - cell.com
Mutations in presenilins are the major cause of familial Alzheimer's disease, but the pathogenic
mechanism by which presenilin mutations cause memory loss and neurodegeneration …
mechanism by which presenilin mutations cause memory loss and neurodegeneration …
Stress duration modulates the spatiotemporal patterns of spine formation in the basolateral amygdala
…, BS McEwen, A Vyas, S Chattarji - Proceedings of the …, 2005 - National Acad Sciences
It has long been hypothesized that morphological and numerical alterations in dendritic spines
underlie long-term structural encoding of experiences. Here we investigate the efficacy of …
underlie long-term structural encoding of experiences. Here we investigate the efficacy of …
[HTML][HTML] Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory
Calcineurin is a calcium-dependent protein phosphatase that has been implicated in various
aspects of synaptic plasticity. By using conditional gene-targeting techniques, we created …
aspects of synaptic plasticity. By using conditional gene-targeting techniques, we created …
Transgenic brain-derived neurotrophic factor expression causes both anxiogenic and antidepressant effects
…, N Mawjee, S Tonegawa, S Chattarji - Proceedings of the …, 2006 - National Acad Sciences
Although neurotrophins have been postulated to have antidepressant properties, their effect
on anxiety is not clear. We find that transgenic overexpression of the neurotrophin BDNF …
on anxiety is not clear. We find that transgenic overexpression of the neurotrophin BDNF …
[PDF][PDF] Altered cortical synaptic morphology and impaired memory consolidation in forebrain-specific dominant-negative PAK transgenic mice
Molecular and cellular mechanisms for memory consolidation in the cortex are poorly known.
To study the relationships between synaptic structure and function in the cortex and …
To study the relationships between synaptic structure and function in the cortex and …
Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice
…, BM Dolan, SY Choi, S Chattarji… - Proceedings of the …, 2007 - National Acad Sciences
Fragile X syndrome (FXS), the most commonly inherited form of mental retardation and autism,
is caused by transcriptional silencing of the fragile X mental retardation 1 (FMR1) gene …
is caused by transcriptional silencing of the fragile X mental retardation 1 (FMR1) gene …