Recent large-scale genomic studies have revealed two broad classes of risk alleles for
schizophrenia: a polygenic component of risk mediated through multiple common risk variants …

Memory reconsolidation is considered to be the process whereby stored memories become
labile on recall, allowing updating. Blocking the restabilization of a memory during …

There is increasing awareness of the role genetic risk variants have in mediating vulnerability
to psychiatric disorders such as schizophrenia and autism. Many of these risk variants …

Chromosomal deletions at Xp22.3 appear to influence vulnerability to the neurodevelopmental
disorders attention deficit hyperactivity disorder (ADHD) and autism. 39,X Y* O mice, …

It is now generally agreed that there are inherent sex differences in healthy individuals
across a number of neurobiological domains (including brain structure, neurochemistry, and …

Alterations in synaptic signaling and plasticity occur during the refinement of neural circuits
over the course of development and the adult processes of learning and memory. Synaptic …

The biological basis of the increased risk for psychiatric disorders seen in 15q11.2 copy
number deletion is unknown. Previous work has shown disturbances in white matter tracts in …

Genes involved in synaptic plasticity, particularly genes encoding postsynaptic density proteins,
have been recurrently linked to psychiatric disorders including schizophrenia and autism…

In addition to their established role in nervous system development, vitamin A and related
retinoids are emerging as regulators of adult brain function. Accutane (13-cis-retinoic acid, …

Attention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental condition
characterised by inattention, impulsivity and hyperactivity; it is frequently co-morbid with …