Esophageal cancer is the eighth most common incident cancer in the world and ranks sixth
among all cancers in mortality. Esophageal cancers are classified into two histological types; …

During the process of metastasis, which is the leading cause of cancer-related death, cancer
cells dissociate from primary tumors, migrate to distal sites, and finally colonize, eventually …

MicroRNAs (miRs) are small RNAs that repress mRNA translation, resulting in the degradation
of mRNAs and regulation of the expression levels of various genes. Recent studies have …

Introduction Our group has conducted extensive basic and preclinical studies of the use of
human induced pluripotent cell (iPSC)-derived neural stem/progenitor cell (hiPSC-NS/PC) …

A primary tumor can create a premetastatic niche in distant organs to facilitate the development
of metastasis. The mechanism by which tumor cells communicate with host cells to …

Fructose-1,6-bisphosphatase (FBP1), the rate-limiting enzyme in gluconeogenesis, is
reduced in expression in certain cancers where it has been hypothesized to act as a tumor …

Programmed death‐ligand 1 ( PD ‐L1) plays a crucial role in the host immune system in cancer
progression. The gene promoter region of PD ‐L1 also contains a binding site for ZEB 1, …

Advanced colorectal cancer harbors extensive intratumor heterogeneity shaped by neutral
evolution; however, intratumor heterogeneity in colorectal precancerous lesions has been …

Tumorigenesis is an important problem that needs to be addressed in the field of human
stem/progenitor cell transplantation for the treatment of subacute spinal cord injury (SCI). When …

Background Global DNA hypomethylation is associated with increased chromosomal
instability and plays an important role in tumorigenesis. The methylation status of the long …