User profiles for Shinya Ito

Shinya Ito

- Verified email at sickkids.ca - Cited by 14138

Shinya Ito

- Verified email at alleninstitute.org - Cited by 1655

Drugs in pregnancy

G Koren, A Pastuszak, S Ito - New England Journal of Medicine, 1998 - Mass Medical Soc
Before marketing a new drug, the manufacturer almost never tests the product in pregnant
women to determine its effects on the fetus. Consequently, most drugs are not labeled for use …

Universal critical dynamics in high resolution neuronal avalanche data

N Friedman, S Ito, BAW Brinkman, M Shimono… - Physical review …, 2012 - APS
The tasks of neural computation are remarkably diverse. To function optimally, neuronal
networks have been hypothesized to operate near a nonequilibrium critical point. However, …

Complete reversal of fatal pulmonary hypertension in rats by a serine elastase inhibitor

KN Cowan, A Heilbut, T Humpl, C Lam, S Ito… - Nature medicine, 2000 - nature.com
Progression of pulmonary hypertension is associated with increased serine elastase activity
and the proteinase-dependent deposition of the extracellular matrix smooth muscle cell …

Drug therapy for breast-feeding women

S Ito - New England Journal of Medicine, 2000 - Mass Medical Soc
Breast-feeding is the best method of feeding neonates and young infants. Its popularity has
increased in recent years, 2 although in 1995 only about 60 percent of new mothers in the …

Local connectivity and synaptic dynamics in mouse and human neocortex

…, T Chartrand, L Kim, A Hoggarth, C Gamlin, S Ito… - Science, 2022 - science.org
We present a unique, extensive, and open synaptic physiology analysis platform and dataset.
Through its application, we reveal principles that relate cell type to synaptic properties and …

Perinatal outcome following third trimester exposure to paroxetine

AM Costei, E Kozer, T Ho, S Ito… - Archives of pediatrics & …, 2002 - jamanetwork.com
Background Paroxetine hydrochloride is commonly used for maternal depression, panic
disorder, and obsessive-compulsive disorder. The drug readily crosses the human placenta. …

[HTML][HTML] Pregnancy-associated changes in pharmacokinetics: a systematic review

…, T Leibson, A Carls, T Adams-Webber, S Ito… - PLoS …, 2016 - journals.plos.org
Background Women are commonly prescribed a variety of medications during pregnancy. As
most organ systems are affected by the substantial anatomical and physiological changes …

[HTML][HTML] Extending transfer entropy improves identification of effective connectivity in a spiking cortical network model

S Ito, ME Hansen, R Heiland, A Lumsdaine, AM Litke… - PloS one, 2011 - journals.plos.org
Transfer entropy (TE) is an information-theoretic measure which has received recent
attention in neuroscience for its potential to identify effective connectivity between neurons. …

Synthesis of new lithium ionic conductor thio-LISICON—lithium silicon sulfides system

M Murayama, R Kanno, M Irie, S Ito, T Hata… - Journal of Solid State …, 2002 - Elsevier
The new lithium ionic conductors, thio-LISICON (LIthium SuperIonic CONductor), were found
in the ternary Li 2 S–SiS 2 –Al 2 S 3 and Li 2 S–SiS 2 –P 2 S 5 systems. Their structures of …

Prospective follow-up of adverse reactions in breast-fed infants exposed to maternal medication

S Ito, A Blajchman, M Stephenson, C Eliopoulos… - American journal of …, 1993 - Elsevier
OBJECTIVE: Our objective was to characterize the short-term effects of maternal medications
on breast-fed infants. STUDY DESIGN: A cohort of 838 infants breast-fed by women who …