Silencing of estrogen receptor α in the ventromedial nucleus of hypothalamus leads to metabolic syndrome
Estrogen receptor α (ERα) plays a pivotal role in the regulation of food intake and energy
expenditure by estrogens. Although it is well documented that a disruption of ERα signaling in …
expenditure by estrogens. Although it is well documented that a disruption of ERα signaling in …
RNAi-mediated silencing of estrogen receptor α in the ventromedial nucleus of hypothalamus abolishes female sexual behaviors
Estrogen receptor α (ERα) plays a major role in the regulation of neuroendocrine functions
and behaviors by estrogens. Although the generation of ERα knockout mice advanced our …
and behaviors by estrogens. Although the generation of ERα knockout mice advanced our …
The role of the estrogen receptor α in the medial amygdala and ventromedial nucleus of the hypothalamus in social recognition, anxiety and aggression
T Spiteri, S Musatov, S Ogawa, A Ribeiro… - Behavioural brain …, 2010 - Elsevier
Social recognition manifests itself in decreased investigation of a previously encountered
individual. Estrogen receptor alpha (ERα) knock out mice show deficient social recognition and …
individual. Estrogen receptor alpha (ERα) knock out mice show deficient social recognition and …
Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens
…, M Vernov, M Stavarache, S Musatov… - Science translational …, 2010 - science.org
The etiology of major depression remains unknown, but dysfunction of serotonergic signaling
has long been implicated in the pathophysiology of this disorder. p11 is an S100 family …
has long been implicated in the pathophysiology of this disorder. p11 is an S100 family …
Differential effects of site‐specific knockdown of estrogen receptor α in the medial amygdala, medial pre‐optic area, and ventromedial nucleus of the hypothalamus on …
K Sano, MC Tsuda, S Musatov… - European Journal of …, 2013 - Wiley Online Library
… Thus, this study employed a virally mediated RNA interference method (Musatov et al., 2006)
… The complete details of the small hairpin RNAs used in this study are described in Musatov …
… The complete details of the small hairpin RNAs used in this study are described in Musatov …
Viral vector-mediated overexpression of estrogen receptor-α in striatum enhances the estradiol-induced motor activity in female rats and estradiol-modulated GABA …
…, AL Bennett, RT Kennedy, S Musatov… - Journal of …, 2009 - Soc Neuroscience
Classical estrogen receptor-signaling mechanisms involve estradiol binding to intracellular
nuclear receptors [estrogen receptor-α (ERα) and estrogen receptor-β (ERβ)] to promote …
nuclear receptors [estrogen receptor-α (ERα) and estrogen receptor-β (ERβ)] to promote …
siRNA silencing of estrogen receptor-α expression specifically in medial preoptic area neurons abolishes maternal care in female mice
AC Ribeiro, S Musatov, A Shteyler… - Proceedings of the …, 2012 - National Acad Sciences
The medial preoptic area has been shown to be intricately involved in many behaviors,
including locomotion, sexual behavior, maternal care, and aggression. The gene encoding …
including locomotion, sexual behavior, maternal care, and aggression. The gene encoding …
Estrogen receptors in the medial amygdala inhibit the expression of male prosocial behavior
Studies using estrogen receptor α (ERα) knock-out mice indicate that ERα masculinizes
male behavior. Recent studies of ERα and male prosocial behavior have shown an inverse …
male behavior. Recent studies of ERα and male prosocial behavior have shown an inverse …
The role of the estrogen receptor α in the medial preoptic area in sexual incentive motivation, proceptivity and receptivity, anxiety, and wheel running in female rats
Ovariectomized females were given an infusion in the medial preoptic area (MPOA) of a viral
vector carrying either a shRNA directed against the estrogen receptor α (ERα) or luciferase. …
vector carrying either a shRNA directed against the estrogen receptor α (ERα) or luciferase. …
Estrogen-induced sexual incentive motivation, proceptivity and receptivity depend on a functional estrogen receptor α in the ventromedial nucleus of the hypothalamus …
The display of copulatory behaviors usually requires the presence of a mate and is, therefore,
preceded by a search for and approach to a potential partner. The intensity of approach …
preceded by a search for and approach to a potential partner. The intensity of approach …