Peripheral nerve injury induces a robust proregenerative program that drives axon
regeneration. While many regeneration-associated genes are known, the mechanisms by which …

Preconditioning nerve injuries activate a pro-regenerative program that enhances axon
regeneration for most classes of sensory neurons. However, nociceptive sensory neurons and …

Axons are unique compartments of neurons that extend tremendous distances throughout
the body. Neurodegenerative or traumatic damage to axons destroys neuronal function and …

Cardiovascular disease affects over 82 million Americans, of which myocardial infarction (MI)
and subsequent heart failure (HF) patients are a major subset. As a result, the …

… , and Scott Karney-Grobe. I would like to thank each individual for undertaking my research
interests with the same dedication and enthusiasm as his or her own. Also from the Mercola …

Ongoing and future initiatives in the search for extraterrestrial intelligence (SETI) will explore
the Galaxy on an unprecedented scale to find evidence of communicating civilizations …

Peripheral nerve injury (PNI) is a common and incurable disease in the clinic, but the effects
of available treatments are still not satisfactory. Therefore, it is necessary to explore new …

Neurons are constantly responding to internal and external cues as they adapt through
signaling cascades and transcriptional programs. I have identified a role for the dual leucine …

The TRPC5 ion channel is activated upon depletion of intracellular calcium stores, as well
as by various stimuli such as nitric oxide (NO), membrane stretch, and cold temperatures. …

10.7554/eLife.14048.001 A broadly known method to stimulate the growth potential of axons
is to elevate intracellular levels of cAMP, however the cellular pathway(s) that mediate this …