Role of the gut microbiota in immunity and inflammatory disease

N Kamada, SU Seo, GY Chen, G Núñez - Nature Reviews Immunology, 2013 - nature.com
The mammalian intestine is colonized by trillions of microorganisms, most of which are bacteria
that have co-evolved with the host in a symbiotic relationship. The collection of microbial …

[PDF][PDF] Cell-type-specific translation profiling reveals a novel strategy for treating fragile X syndrome

SR Thomson, SS Seo, SA Barnes, SR Louros… - Neuron, 2017 - cell.com
Excessive mRNA translation downstream of group I metabotropic glutamate receptors (mGlu
1/5 ) is a core pathophysiology of fragile X syndrome (FX); however, the differentially …

Cytotoxic T lymphocytes are critical in the control of infectious bronchitis virus in poultry

EW Collisson, J Pei, J Dzielawa, SH Seo - Developmental & Comparative …, 2000 - Elsevier
… The carboxyl terminus of the nucleocapsid protein houses an epitope(s) responsible for
induction of CTL responses to IBV N protein. Inoculation of DNA plasmid expressing the …

Sentinel lymph node biopsy in endometrial cancer: meta-analysis of 26 studies

S Kang, HJ Yoo, JH Hwang, MC Lim, SS Seo… - Gynecologic …, 2011 - Elsevier
OBJECTIVE: The validity of the sentinel lymph node (SLN) procedure for the assessment of
nodal status in patients with endometrial cancer is unclear. We aimed to assess the …

[HTML][HTML] Excess ribosomal protein production unbalances translation in a model of Fragile X Syndrome

SS Seo, SR Louros, N Anstey… - Nature …, 2022 - nature.com
Dysregulated protein synthesis is a core pathogenic mechanism in Fragile X Syndrome (FX).
The mGluR Theory of FX predicts that pathological synaptic changes arise from the …

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

…, I Santana, M Sarazin, J Schröder, C Schütte, SW Seo… - Jama, 2015 - jamanetwork.com
Importance Cerebral amyloid-β aggregation is an early pathological event in Alzheimer
disease (AD), starting decades before dementia onset. Estimates of the prevalence of amyloid …

[PDF][PDF] Excessive proteostasis contributes to pathology in fragile X syndrome

SR Louros, SS Seo, B Maio, C Martinez-Gonzalez… - Neuron, 2023 - cell.com
In fragile X syndrome (FX), the leading monogenic cause of autism, excessive neuronal protein
synthesis is a core pathophysiology; however, an overall increase in protein expression …

Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease

…, P Ramachandran, A Pellicoro, RA Ridgway, SS Seo… - Nature medicine, 2012 - nature.com
During chronic injury a population of bipotent hepatic progenitor cells (HPCs) become activated
to regenerate both cholangiocytes and hepatocytes. Here we show in human diseased …

Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis

…, VL Villemagne, CC Rowe, DY Lee, DL Na, SW Seo… - Jama, 2015 - jamanetwork.com
Importance Amyloid-β positron emission tomography (PET) imaging allows in vivo detection
of fibrillar plaques, a core neuropathological feature of Alzheimer disease (AD). Its …

[HTML][HTML] Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein

S Seo, P McNamara, S Heo, A Turner, WS Lane… - Cell, 2001 - cell.com
Acetylation of histones by p300/CBP and PCAF is considered to be a critical step in transcriptional
regulation. In order to understand the role of cellular activities that modulate histone …