User profiles for S. Richhariya

Shlesha Richhariya

- Verified email at brandeis.edu - Cited by 192

Shakshi Richhariya

- Verified email at sjsu.edu

Store-operated calcium entry through Orai is required for transcriptional maturation of the flight circuit in Drosophila

…, T Agrawal, S Richhariya, S Sadaf… - Journal of …, 2015 - Soc Neuroscience
… All videos were recorded for 30 s after flight initiation at 24 frames per second. The 30 s time
period was based on our observation that flies exhibiting 30 s flight bouts usually continued …

Dopamine and GPCR-mediated modulation of DN1 clock neurons gates the circadian timing of sleep

M Schlichting, S Richhariya… - Proceedings of the …, 2022 - National Acad Sciences
… Dop1R1 and Dop1R2 are coupled to G S and lead to increases in cAMP, whereas Dop2R
is coupled to an inhibitory G protein (G i ) (6). Similarly, most GPCRs directly influence the …

Dissecting neuron-specific functions of circadian genes using modified cell-specific CRISPR approaches

S Richhariya, D Shin, JQ Le… - Proceedings of the …, 2023 - National Acad Sciences
… , Kruskal–Wallis test followed by a post hoc Dunn’s test. (C–E) Actograms represent double-…
statistically distinct groups; P < 0.01, Kruskal–Wallis test followed by a post hoc Dunn’s test. …

Drosophila larval to pupal switch under nutrient stress requires IP3R/Ca2+ signalling in glutamatergic interneurons

S Jayakumar, S Richhariya, OV Reddy, MJ Texada… - Elife, 2016 - elifesciences.org
… The circuit of neurons within the larval nervous system that detects external nutrient levels,
and then relays that information to the insect’s metabolic system, remains unknown. This …

[HTML][HTML] A pupal transcriptomic screen identifies Ral as a target of store-operated calcium entry in Drosophila neurons

S Richhariya, S Jayakumar, K Abruzzi, M Rosbash… - Scientific reports, 2017 - nature.com
… indistinguishable groups (one-way ANOVA with a post hoc Tukey’s test p < 0.05). … ) was
performed, followed by pairwise Tukey’s test. Statistical significance post ANOVA is denoted with …

A multicomponent neuronal response encodes the larval decision to pupariate upon amino acid starvation

S Jayakumar, S Richhariya, BK Deb… - Journal of …, 2018 - Soc Neuroscience
… Mechanism(s) that stimulate appropriate cellular responses and allow normal development
on a nutritionally deficient diet remain to be understood. Here, we demonstrate that …

[HTML][HTML] Loss of IP3 receptor function in neuropeptide secreting neurons leads to obesity in adult Drosophila

M Subramanian, S Jayakumar, S Richhariya… - BMC neuroscience, 2013 - Springer
… p < 0.05; Student’s t test; difference significant as compared to the corresponding time point
of the … p < 0.05; Student’s t test; difference significant as compared to the wild type unless …

Orai-mediated calcium entry determines activity of central dopaminergic neurons by regulation of gene expression

R Mitra, S Richhariya, G Hasan - Elife, 2024 - elifesciences.org
… The online version of this article includes the following source data and figure supplement(s
The online version of this article includes the following source data and figure supplement(s) …

[HTML][HTML] Orai mediated Calcium entry sets the excitability threshold of central dopaminergic neurons by regulation of gene expression

R Mitra, S Richhariya, G Hasan - eLife, 2023 - elifesciences.org
… In C and D flight bout durations in seconds (s) are represented as a swarm plot where each
… difference for comparisons against the shared Canton S control and is shown as a Cumming …

dSTIM-and ral/Exocyst-Mediated synaptic release from pupal dopaminergic neurons sustains Drosophila Flight

S Richhariya, S Jayakumar, SK Sukumar, G Hasan - eneuro, 2018 - eneuro.org
… Images were taken as a time series across depth at an interval of 4 s using a 10ื objective
with … from 60 to 300 s for saline-induced release and from 300 to 600 s for evoked release by …