User profiles for Ryan G. Parsons
Ryan ParsonsStony Brook University Verified email at stonybrook.edu Cited by 1796 |
Implications of memory modulation for post-traumatic stress and fear disorders
RG Parsons, KJ Ressler - Nature neuroscience, 2013 - nature.com
Post-traumatic stress disorder, panic disorder and phobia manifest in ways that are
consistent with an uncontrollable state of fear. Their development involves heredity, previous …
consistent with an uncontrollable state of fear. Their development involves heredity, previous …
Translational control via the mammalian target of rapamycin pathway is critical for the formation and stability of long-term fear memory in amygdala neurons
RG Parsons, GM Gafford… - Journal of …, 2006 - Soc Neuroscience
The mammalian target of rapamycin kinase (mTOR) regulates protein synthesis in neurons
at the translational level through phosphorylation of several intracellular targets. Recent work …
at the translational level through phosphorylation of several intracellular targets. Recent work …
Consolidation and reconsolidation of contextual fear memory requires mammalian target of rapamycin-dependent translation in the dorsal hippocampus
The mammalian target of rapamycin (mTOR) pathway is important for regulating protein
translation. The present study characterized the role of mTOR-dependent translation in the …
translation. The present study characterized the role of mTOR-dependent translation in the …
Differential expression of cytoskeletal regulatory factors in the adolescent prefrontal cortex: implications for cortical development
LP Shapiro, RG Parsons, AJ Koleske… - Journal of …, 2017 - Wiley Online Library
The prevalence of depression, anxiety, schizophrenia, and drug and alcohol use disorders
peaks during adolescence. Further, up to 50% of “adult” mental health disorders emerge in …
peaks during adolescence. Further, up to 50% of “adult” mental health disorders emerge in …
Macromolecular synthesis, distributed synaptic plasticity, and fear conditioning
Recent work from a number of laboratories has provided new and important insights about
how gene expression is altered by experience and how these molecular changes may …
how gene expression is altered by experience and how these molecular changes may …
Long‐term stability of fear memory depends on the synthesis of protein but not mRNA in the amygdala
RG Parsons, GM Gafford, DE Baruch… - European Journal of …, 2006 - Wiley Online Library
Synaptic modification supporting memory formation is thought to depend on gene expression
and protein synthesis. Disrupting either process around the time of learning prevents the …
and protein synthesis. Disrupting either process around the time of learning prevents the …
Response-specific sex difference in the retention of fear extinction
ME Voulo, RG Parsons - Learning & Memory, 2017 - learnmem.cshlp.org
Fear conditioning studies in rodents allow us to assess vulnerability factors which might
underlie fear-based psychopathology such as post-traumatic stress disorder (PTSD). Despite …
underlie fear-based psychopathology such as post-traumatic stress disorder (PTSD). Despite …
The timing of multiple retrieval events can alter GluR1 phosphorylation and the requirement for protein synthesis in fear memory reconsolidation
Numerous studies have indicated that maintaining a fear memory after retrieval requires de
novo protein synthesis. However, no study to date has examined how the temporal dynamics …
novo protein synthesis. However, no study to date has examined how the temporal dynamics …
Temporary disruption of fear-potentiated startle following PKMζ inhibition in the amygdala
RG Parsons, M Davis - Nature neuroscience, 2011 - nature.com
We examined whether protein kinase M zeta (PKMζ) inhibition in the amygdala permanently
disrupts fear memory by testing retention at various intervals after PKMζ blockade. Although …
disrupts fear memory by testing retention at various intervals after PKMζ blockade. Although …
[HTML][HTML] Behavioral expression of contextual fear in male and female rats
AS Russo, RG Parsons - Frontiers in Behavioral Neuroscience, 2021 - frontiersin.org
The study of fear conditioning has led to a better understanding of fear and anxiety-based
disorders such as post-traumatic stress disorder (PTSD). Despite the fact many of these …
disorders such as post-traumatic stress disorder (PTSD). Despite the fact many of these …