Multiple sclerosis (MS) is a disease characterized by inflammation and demyelination. Currently,
the cause of MS is unknown. Experimental autoimmune encephalomyelitis (EAE) is the …

Estrogen has well-documented neuroprotective effects in a variety of clinical and experimental
disorders of the CNS, including autoimmune inflammation, traumatic injury, stroke, and …

Estrogens can signal through either estrogen receptor α (ERα) or β (ERβ) to ameliorate
experimental autoimmune encephalomyelitis (EAE), the most widely used mouse model of …

Gray matter atrophy has been shown to be a strong correlate to clinical disability in multiple
sclerosis (MS) and its most commonly used animal model, experimental autoimmune …

Sex steroids assist adult neural tissue in the protection from and repair of damage resulting
from neural injury; some steroids may be synthesized in the brain. Songbirds are especially …

Context: Glucocorticoids (GC) are powerful endogenous and therapeutic modulators of
inflammation and play a critical role for controlling autoimmunity. GC resistance can be seen in …

In addition to its key role in complex motor function, the cerebellum is increasingly recognized
to have a role in cognition. Songbirds are particularly good models for the investigation of …

Multiple sclerosis (MS) is an autoimmune disease characterized by inflammation and
neurodegeneration. Current MS treatments were designed to reduce inflammation in MS rather …

Mild traumatic brain injuries (mTBIs) are one of the most prevalent neurological disorders,
and humans are severely limited in their ability to repair and regenerate central nervous …

Traditionally, tissue visualization has required that the tissue of interest be serially sectioned
and imaged, subjecting each tissue section to unique non-linear deformations, dramatically …