User profiles for Roger C. Hardie
Prof RC HardieVerified email at cam.ac.uk Cited by 14613 |
The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors
Invertebrate phototransduction is an important model system for studying the ubiquitous
inositol-lipid signaling system. In the transient receptor potential (trp) mutant, one of the most …
inositol-lipid signaling system. In the transient receptor potential (trp) mutant, one of the most …
Visual transduction in Drosophila
The brain's capacity to analyse and interpret information is limited ultimately by the input it
receives. This sets a premium on information capacity of sensory receptors, which can be …
receives. This sets a premium on information capacity of sensory receptors, which can be …
[HTML][HTML] Phototransduction motifs and variations
Seeing begins in the photoreceptors, where light is absorbed and signaled to the nervous
system. Throughout the animal kingdom, photoreceptors are diverse in design and purpose. …
system. Throughout the animal kingdom, photoreceptors are diverse in design and purpose. …
Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL
Phototransduction in invertebrate microvillar photoreceptors is thought to be mediated by
the activation of phospholipase C (PLC), but how this leads to gating of the light-sensitive …
the activation of phospholipase C (PLC), but how this leads to gating of the light-sensitive …
Functional organization of the fly retina
RC Hardie - Progress in sensory physiology, 1985 - Springer
Practically no other invertebrate has been used so extensively for the investigation of the visual
system as the fly, particularly the genera Musca, Calliphora and Drosophila. The reasons …
system as the fly, particularly the genera Musca, Calliphora and Drosophila. The reasons …
A histamine-activated chloride channel involved in neurotransmission at a photoreceptor synapse
RC Hardie - Nature, 1989 - nature.com
COMPARED with the variety of neuromodulatory agents acting through second messenger
systems, the number of fast neurotran-smitters which directly activate ion channels is limited. …
systems, the number of fast neurotran-smitters which directly activate ion channels is limited. …
Common strategies for light adaptation in the peripheral visual systems of fly and dragonfly
SB Laughlin, RC Hardie - Journal of comparative physiology, 1978 - Springer
Intracellular recordings from photoreceptors and large monopolar cells (LMC's) of the
flyCalliphora stygia, and the dragonflyHemicordulia tau, were used to examine the peripheral light …
flyCalliphora stygia, and the dragonflyHemicordulia tau, were used to examine the peripheral light …
The photoreceptor array of the dipteran retina
RC Hardie - Trends in Neurosciences, 1986 - cell.com
The regular facetted appearance of the dipteran compound eye conceals an equally regular
array of photoreceptors and interneurons that constitutes one of the most thoroughly …
array of photoreceptors and interneurons that constitutes one of the most thoroughly …
Photomechanical Responses in Drosophila Photoreceptors
Phototransduction in Drosophila microvillar photoreceptor cells is mediated by a G protein–activated
phospholipase C (PLC). PLC hydrolyzes the minor membrane lipid …
phospholipase C (PLC). PLC hydrolyzes the minor membrane lipid …
Phototransduction in Drosophila melanogaster
RC Hardie - Journal of Experimental Biology, 2001 - journals.biologists.com
As in most invertebrate microvillar photoreceptors, phototransduction in Drosophila
melanogaster uses a G-protein-coupled phosphoinositide pathway, whereby hydrolysis of …
melanogaster uses a G-protein-coupled phosphoinositide pathway, whereby hydrolysis of …