User profiles for Rhushikesh A. Phadke

Rhushikesh Phadke

PhD Student, Boston University
Verified email at bu.edu
Cited by 147

[HTML][HTML] Increased expression of schizophrenia-associated gene C4 leads to hypoconnectivity of prefrontal cortex and reduced social interaction

AL Comer, T Jinadasa, B Sriram, RA Phadke… - PLoS …, 2020 - journals.plos.org
Schizophrenia is a severe mental disorder with an unclear pathophysiology. Increased
expression of the immune gene C4 has been linked to a greater risk of developing schizophrenia…

Sex differences in behavioral and brainstem transcriptomic neuroadaptations following neonatal opioid exposure in outbred mice

KN Borrelli, EJ Yao, WW Yen, RA Phadke, QT Ruan… - ENeuro, 2021 - eneuro.org
The opioid epidemic led to an increase in the number of neonatal opioid withdrawal syndrome
(NOWS) cases in infants born to opioid-dependent mothers. Hallmark features of NOWS …

Highly unstable heterogeneous representations in VIP interneurons of the anterior cingulate cortex

…, A O'Connor, RS Liu, JC Jimenez, RA Phadke… - Molecular …, 2022 - nature.com
A hallmark of the anterior cingulate cortex (ACC) is its functional heterogeneity. Functional
and imaging studies revealed its importance in the encoding of anxiety-related and social …

[HTML][HTML] C4 induces pathological synaptic loss by impairing AMPAR trafficking

RA Phadke, E Kruzich, LA Fournier, A Brack, M Sha… - bioRxiv, 2023 - ncbi.nlm.nih.gov
During development, activation of the complement pathway, an extracellular proteolytic
cascade, results in microglia-dependent synaptic elimination via complement receptor 3 (CR3). …

[HTML][HTML] A pipeline for STED super-resolution imaging and Imaris analysis of nanoscale synapse organization in mouse cortical brain slices

E Kruzich, RA Phadke, A Brack, D Stroumbakis… - STAR protocols, 2023 - Elsevier
Advances in super-resolution imaging enable us to delve into its intricate structural and
functional complexities with unprecedented detail. Here, we present a pipeline to visualize and …

Overexpression of the schizophrenia risk gene C4 in PV cells drives sex-dependent behavioral deficits and circuit dysfunction.

LA Fournier, RA Phadke, M Salgado, A Brack… - bioRxiv, 2024 - biorxiv.org
Fast-spiking parvalbumin (PV)-positive cells are key players in orchestrating pyramidal
neuron activity and thus serve an indispensable role in cognitive function and emotional …

[HTML][HTML] REVEALS: An Open Source Multi Camera GUI For Rodent Behavior Acquisition

RA Phadke, AM Wetzel, LA Fournier, M Sha… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Understanding the rich behavioral data generated by mice is essential for deciphering the
function of the healthy and diseased brain. However, the current landscape lacks effective, …

Collaborating Reviewers

…, M Moisa, K Montgomery, K Nasrallah, R Phadke… - eneuro.org
… Christopher Knowlton Michelle Krumm Kaho Magami Bhagaban Mallik David Martin
Anas Masood Jessica Mella Hagar Meltzer Jennifer Minteer Marius Moisa Kristen …

[HTML][HTML] Quantification of bacterial fluorescence using independent calibrants

J Beal, T Haddock-Angelli, G Baldwin, M Gershater… - PloS one, 2018 - journals.plos.org
Fluorescent reporters are commonly used to quantify activities or properties of both natural
and engineered cells. Fluorescence is still typically reported only in arbitrary or normalized …

[PDF][PDF] S1 File: Consortium Author List

J Beal, GS Baldwin, NG Farny, M Gershater… - authors.library.caltech.edu
Consortium authors include all persons identified by contributing teams as deserving co-authorship
credit. Contributors are listed alphabetically within team, and teams alphabetically. …