[HTML][HTML] Deficient sleep in mouse models of fragile X syndrome
RM Saré, L Harkless, M Levine, A Torossian… - Frontiers in molecular …, 2017 - frontiersin.org
In patients with fragile X syndrome (FXS), sleep problems are commonly observed but are
not well characterized. In animal models of FXS (dfmr1 and Fmr1 knockout (KO)/Fxr2 …
not well characterized. In animal models of FXS (dfmr1 and Fmr1 knockout (KO)/Fxr2 …
Chronic sleep restriction during development can lead to long-lasting behavioral effects
RM Saré, M Levine, C Hildreth, D Picchioni… - Physiology & …, 2016 - Elsevier
… (# 8679) from Autism Speaks awarded to R. Michelle Reith (Saré), and a summer fellowship
from the Irene & Eric Simon Brain Research Foundation awarded to Christine Hildreth. …
from the Irene & Eric Simon Brain Research Foundation awarded to Christine Hildreth. …
Behavioral phenotype of Fmr1 knock-out mice during active phase in an altered light/dark cycle
RM Saré, M Levine, CB Smith - Eneuro, 2016 - eneuro.org
Fragile X syndrome (FXS) is the most commonly inherited form of intellectual disability and is
a disorder that is also highly associated with autism. FXS occurs as a result of an expanded …
a disorder that is also highly associated with autism. FXS occurs as a result of an expanded …
Chronic sleep deprivation in mouse pups by means of gentle handling
A Lemons, RM Saré, CB Smith - JoVE (Journal of Visualized Experiments), 2018 - jove.com
Sleep is critical for proper development and neural plasticity. Moreover, abnormal sleep
patterns are characteristic of many neurodevelopmental disorders. Studying how chronic sleep …
patterns are characteristic of many neurodevelopmental disorders. Studying how chronic sleep …
[HTML][HTML] Behavior testing in rodents: highlighting potential confounds affecting variability and reproducibility
RM Saré, A Lemons, CB Smith - Brain sciences, 2021 - mdpi.com
Rodent models of brain disorders including neurodevelopmental, neuropsychiatric, and
neurodegenerative diseases are essential for increasing our understanding of underlying …
neurodegenerative diseases are essential for increasing our understanding of underlying …
[HTML][HTML] Behavioral phenotype in the TgF344-AD rat model of Alzheimer's disease
RM Saré, SK Cooke, L Krych, PM Zerfas… - Frontiers in …, 2020 - frontiersin.org
Alzheimer’s disease (AD) is a progressive neurodegenerative disease resulting in cognitive
decline. A unique rat model, TgF344-AD, recapitulates pathological hallmarks of AD. We …
decline. A unique rat model, TgF344-AD, recapitulates pathological hallmarks of AD. We …
Noninvasive, high-throughput determination of sleep duration in rodents
RM Saré, A Lemons, A Torossian, CB Smith - JoVE (Journal of Visualized …, 2018 - jove.com
Traditionally, sleep is monitored by an electroencephalogram (EEG). EEG studies in rodents
require surgical implantation of the electrodes followed by a long recovery period. To …
require surgical implantation of the electrodes followed by a long recovery period. To …
Diaschisis: An old concept brought to new life
RM Saré - Journal of Neuroscience, 2016 - Soc Neuroscience
… This work was not written as part of R. Michelle Saré's official duties. The views expressed
in this article do not necessarily represent the views of the NIMH, NIH, HHS, or the United …
in this article do not necessarily represent the views of the NIMH, NIH, HHS, or the United …
Association between sleep deficiencies with behavioral problems in autism spectrum disorder: subtle sex differences
RM Saré, CB Smith - Autism Research, 2020 - Wiley Online Library
Sleep problems are prevalent in people with autism spectrum disorder (ASD). Several
studies have shown an association between sleep problems and severity of ASD‐related …
studies have shown an association between sleep problems and severity of ASD‐related …
[HTML][HTML] Increased rates of cerebral protein synthesis in Shank3 knockout mice: Implications for a link between synaptic protein deficit and dysregulated protein …
A Torossian, RM Saré, I Loutaev, CB Smith - Neurobiology of Disease, 2021 - Elsevier
… rCPS was computed by means of the operational equation(1) R i = P i ∗ T λ i ∫ 0 T C p ∗
t C p dt where R i is the rate of incorporation of leucine into tissue protein, P i ⁎ (T) is the …
t C p dt where R i is the rate of incorporation of leucine into tissue protein, P i ⁎ (T) is the …