In patients with fragile X syndrome (FXS), sleep problems are commonly observed but are
not well characterized. In animal models of FXS (dfmr1 and Fmr1 knockout (KO)/Fxr2 …

… (# 8679) from Autism Speaks awarded to R. Michelle Reith (Saré), and a summer fellowship
from the Irene & Eric Simon Brain Research Foundation awarded to Christine Hildreth. …

Fragile X syndrome (FXS) is the most commonly inherited form of intellectual disability and is
a disorder that is also highly associated with autism. FXS occurs as a result of an expanded …

Sleep is critical for proper development and neural plasticity. Moreover, abnormal sleep
patterns are characteristic of many neurodevelopmental disorders. Studying how chronic sleep …

Rodent models of brain disorders including neurodevelopmental, neuropsychiatric, and
neurodegenerative diseases are essential for increasing our understanding of underlying …

Alzheimer’s disease (AD) is a progressive neurodegenerative disease resulting in cognitive
decline. A unique rat model, TgF344-AD, recapitulates pathological hallmarks of AD. We …

Traditionally, sleep is monitored by an electroencephalogram (EEG). EEG studies in rodents
require surgical implantation of the electrodes followed by a long recovery period. To …

… This work was not written as part of R. Michelle Saré's official duties. The views expressed
in this article do not necessarily represent the views of the NIMH, NIH, HHS, or the United …

Sleep problems are prevalent in people with autism spectrum disorder (ASD). Several
studies have shown an association between sleep problems and severity of ASD‐related …

… rCPS was computed by means of the operational equation(1) R i = P i ∗ T λ i ∫ 0 T C p ∗
t C p dt where R i is the rate of incorporation of leucine into tissue protein, P i ⁎ (T) is the …