User profiles for R. Cools
Roshan CoolsProfessor of Cognitive Neuropsychiatry, Radboud University Nijmegen Verified email at donders.ru.nl Cited by 23757 |
Inverted-U–shaped dopamine actions on human working memory and cognitive control
R Cools, M D'Esposito - Biological psychiatry, 2011 - Elsevier
Brain dopamine (DA) has long been implicated in cognitive control processes, including
working memory. However, the precise role of DA in cognition is not well-understood, partly …
working memory. However, the precise role of DA in cognition is not well-understood, partly …
Dopaminergic modulation of cognitive function-implications for L-DOPA treatment in Parkinson's disease
R Cools - Neuroscience & Biobehavioral Reviews, 2006 - Elsevier
It is well recognised that patients with Parkinson's disease exhibit cognitive deficits, even in
the earliest disease stages. Whereas, l-DOPA therapy in early Parkinson's disease is …
the earliest disease stages. Whereas, l-DOPA therapy in early Parkinson's disease is …
The neuropsychology of ventral prefrontal cortex: decision-making and reversal learning
Converging evidence from human lesion, animal lesion, and human functional neuroimaging
studies implicates overlapping neural circuitry in ventral prefrontal cortex in decision-…
studies implicates overlapping neural circuitry in ventral prefrontal cortex in decision-…
Enhanced or impaired cognitive function in Parkinson's disease as a function of dopaminergic medication and task demands
We investigated how dopamine (DA) systems contribute to cognitive performance in the
domain of learning and attentional flexibility by examining effects of withdrawing DA-ergic …
domain of learning and attentional flexibility by examining effects of withdrawing DA-ergic …
Defining the neural mechanisms of probabilistic reversal learning using event-related functional magnetic resonance imaging
Event-related functional magnetic resonance imaging was used to measure blood oxygenation
level-dependent responses in 13 young healthy human volunteers during performance …
level-dependent responses in 13 young healthy human volunteers during performance …
L-Dopa medication remediates cognitive inflexibility, but increases impulsivity in patients with Parkinson's disease
In the current study we investigated the role of dopamine in attentional and socio-emotional
functioning by examining effects of withdrawing dopaminergic medication in patients with …
functioning by examining effects of withdrawing dopaminergic medication in patients with …
Serotoninergic regulation of emotional and behavioural control processes
5-Hydroxytryptamine (5-HT, serotonin) has long been implicated in a wide variety of emotional,
cognitive and behavioural control processes. However, its precise contribution is still not …
cognitive and behavioural control processes. However, its precise contribution is still not …
[HTML][HTML] Mechanisms of motivation–cognition interaction: challenges and opportunities
Recent years have seen a rejuvenation of interest in studies of motivation–cognition interactions
arising from many different areas of psychology and neuroscience. The present issue of …
arising from many different areas of psychology and neuroscience. The present issue of …
Mechanisms of cognitive set flexibility in Parkinson's disease
… Cools AR. Role of the neostriatal dopaminergic activity in sequencing and selecting
behavioural strategies: facilitation of processes involved in selecting the best strategy in a stressful …
behavioural strategies: facilitation of processes involved in selecting the best strategy in a stressful …
Dopaminergic modulation of high‐level cognition in Parkinson's disease: the role of the prefrontal cortex revealed by PET
This study examined the effects of l‐dopa medication in patients with Parkinson’s disease on
cortical and subcortical blood flow changes during two tasks known to involve frontostriatal …
cortical and subcortical blood flow changes during two tasks known to involve frontostriatal …