… There he worked in Professor Linhardt's research group studying the glycosaminoglycan
structure and its interaction with proteins and enzymes. Ishan Capila has recently joined …

Although interactions of proteins with glycosaminoglycans (GAGs), such as heparin and
heparan sulphate, are of great biological importance, structural requirements for protein‐GAG …

… Lohse DL, Linhardt RJ. Purification and characterization of hep… Linhardt RJ. Chemical
and enzymatic methods for the … Rice KG, Kim YS, Grant AC, Merchant ZM, Linhardt RJ. High…

The crystal structure of a dimeric 2:2:2 FGF:FGFR:heparin ternary complex at 3 Å resolution
has been determined. Within each 1:1 FGF:FGFR complex, heparin makes numerous …

Dengue virus is a human pathogen that has reemerged as an increasingly important public
health threat. We found that the cellular receptor utilized by dengue envelope protein to bind …

There is strong recent interest in ultrathin, flexible, safe energy storage devices to meet the
various design and power needs of modern gadgets. To build such fully flexible and robust …

Lignocellulose represents a key sustainable source of biomass for transformation into biofuels
and bio‐based products. Unfortunately, lignocellulosic biomass is highly recalcitrant to …

Crystal structures of heparin-derived tetra- and hexasaccharides complexed with basic
fibroblast growth factor (bFGF) were determined at resolutions of 1.9 and 2.2 angstroms, …

Heparin or a heparin fragment administered with cortisone inhibited angiogenesis, caused
regression of large tumor masses, and prevented metastases. Oral administration of heparin …

… Rice KG, Rottink MK, Linhardt RJ: Fractionation of heparin-derived oligosaccharides by
gradient polyacrylamide-gel electrophoresis. Biochem J 244:515, 1987 25. Merchant ZM, Kim YS…