Neural control of the function of visceral organs is essential for homeostasis and health.
Intestinal peristalsis is critical for digestive physiology and host defence, and is often …

Macrophages are highly heterogeneous tissue-resident immune cells that perform a variety
of tissue-supportive functions. The current paradigm dictates that intestinal macrophages are …

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder due
to selective loss of motor neurons (MNs). Mutations in the fused in sarcoma (FUS) gene can …

… Declaration of personal interests: Pieter Janssen is a research fellow of the ‘Fonds voor
Wetenschappelijk onderzoek – Vlaanderen, Belgium’. This work was supported by an FWO …

… Pieter Vanden Berghe and Vassilis Pachnis are co-… Pieter Vanden Berghe and Vassilis
Pachnis are co-corresponding … Pieter Vanden Berghe and Vassilis Pachnis are co-corresponding …

TDP‐43 is the major component of pathological inclusions in most ALS patients and in up to
50% of patients with frontotemporal dementia (FTD). Heterozygous missense mutations in …

Charcot-Marie-Tooth disease (CMT) is the most common inherited disorder of the peripheral
nervous system. Mutations in the 27-kDa small heat-shock protein gene (HSPB1) cause …

The cholinergic anti-inflammatory pathway (CAIP) has been proposed as a key mechanism
by which the brain, through the vagus nerve, modulates the immune system in the spleen. …

The enteric nervous system (ENS) in mammals forms from neural crest cells during
embryogenesis and early postnatal life. Nevertheless, multipotent progenitors of the ENS can be …

Background & Aims Histamine sensitizes the nociceptor transient reporter potential channel
V1 (TRPV1) and has been shown to contribute to visceral hypersensitivity in animals. We …