User profiles for Philip A. Barker

Philip A Barker

Professor of Biology, University of British Columbia
Verified email at ubc.ca
Cited by 15648

The Tidal Commitments: extending the value base of mental health recovery

P BUCHANAN‐BARKER… - Journal of Psychiatric and …, 2008 - Wiley Online Library
The emerging concept of recovery in mental health is often only loosely defined, but appears
to be influenced more by specific human values and beliefs, than scientific research and ‘…

Determining the impact of distributed generation on power systems. I. Radial distribution systems

PP Barker, RW De Mello - 2000 Power Engineering Society …, 2000 - ieeexplore.ieee.org
Distributed generation (DG) has much potential to improve distribution system performance
and it should be encouraged. However, distribution system designs and operating practices …

[HTML][HTML] cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

…, J Durkin, JW Gillard, JB Jaquith, SJ Morris, PA Barker - Molecular cell, 2008 - cell.com
The inhibitor of apoptosis (IAP) family of proteins enhances cell survival through mechanisms
that remain uncertain. In this report, we show that cIAP1 and cIAP2 promote cancer cell …

Neurotrophin signaling through the p75 neurotrophin receptor

PP Roux, PA Barker - Progress in neurobiology, 2002 - Elsevier
The neurotrophins are growth factors that play critical roles in the development, maintenance,
survival, and death of the nervous system. The signal transducing systems that mediate …

[BOOK][B] The Tidal Model: A guide for mental health professionals

PJ Barker, P Buchanan-Barker - 2005 - books.google.com
… I first came to know Dr Phil Barker when we were both members of the 'Madness' internet …
impressed by the respect and interest that Dr Barker brought to the discussion as a psychiatric …

De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia

…, EA Stone, P Awadalla, PA Barker… - Proceedings of the …, 2010 - National Acad Sciences
Schizophrenia likely results from poorly understood genetic and environmental factors. We
studied the gene encoding the synaptic protein SHANK3 in 285 controls and 185 …

Constitutive nuclear factor-κB activity is required for central neuron survival

…, DS Park, S MacPherson, PA Barker - Journal of …, 2002 - Soc Neuroscience
The function of nuclear factor (NF)-κB within the developing and mature CNS is controversial.
We have generated transgenic mice to reveal NF-κB transcriptional activity in vivo. As …

Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells

PA Barker, EM Shooter - Neuron, 1994 - cell.com
The role of the low affinity neurotrophin receptor, p75LNT’, in NGF-mediated signal
transduction has been examined. Our results show that treatment of PC12 cells with MC192, a …

The MAGE proteins: emerging roles in cell cycle progression, apoptosis, and neurogenetic disease

PA Barker, A Salehi - Journal of neuroscience research, 2002 - Wiley Online Library
Since the identification of the first MAGE gene in 1991, the MAGE family has expanded
dramatically, and over 25 MAGE genes have now been identified in humans. The focus of studies …

Vasculature guides migrating neuronal precursors in the adult mammalian forebrain via brain-derived neurotrophic factor signaling

…, C Gravel, F Berthod, M Götz, PA Barker… - Journal of …, 2009 - Soc Neuroscience
Adult neuronal precursors retain the remarkable capacity to migrate long distances from the
posterior (subventricular zone) to the most anterior [olfactory bulb (OB)] parts of the brain. …