User profiles for Oren Princz-Lebel

Oren Princz-Lebel

PhD Candidate, Western University
Verified email at uwo.ca
Cited by 110

[HTML][HTML] Age-dependent and region-specific alteration of parvalbumin neurons, perineuronal nets and microglia in the mouse prefrontal cortex and hippocampus …

AC Reichelt, CA Lemieux, O Princz-Lebel, A Singh… - Scientific reports, 2021 - nature.com
Emergent evidence demonstrates that excessive consumption of high fat and high sugar (HFHS)
diets has negative consequences on hippocampal and prefrontal cortex (PFC) function. …

Temporal Dynamics Underlying Prelimbic Prefrontal Cortical Regulation of Action Selection and Outcome Evaluation during Risk/Reward Decision-Making

DA Bercovici, O Princz-Lebel… - Journal of …, 2023 - Soc Neuroscience
Risk/reward decision-making is a dynamic process that includes periods of deliberation
before action selection and evaluation of the action outcomes that bias subsequent choices. …

[HTML][HTML] Continuous cholinergic-dopaminergic updating in the nucleus accumbens underlies approaches to reward-predicting cues

M Skirzewski, O Princz-Lebel… - Nature …, 2022 - nature.com
The ability to learn Pavlovian associations from environmental cues predicting positive
outcomes is critical for survival, motivating adaptive behaviours. This cued-motivated behaviour …

Optogenetic dissection of temporal dynamics of amygdala-striatal interplay during risk/reward decision making

DA Bercovici, O Princz-Lebel, TT Maric, DE Moorman… - Eneuro, 2018 - eneuro.org
Decision making often requires weighing costs and benefits of different options that vary in
terms of reward magnitude and uncertainty. Previous studies using pharmacological …

Hippocampal neurogenesis promotes preference for future rewards

DR Seib, DF Espinueva, O Princz-Lebel… - Molecular …, 2021 - nature.com
Adult hippocampal neurogenesis has been implicated in a number of disorders where
reward processing is disrupted but whether new neurons regulate specific aspects of reward-…

[HTML][HTML] Intact memory for local and distal cues in male and female rats that lack adult neurogenesis

DR Seib, E Chahley, O Princz-Lebel, JS Snyder - PLoS One, 2018 - journals.plos.org
The dentate gyrus is essential for remembering the fine details of experiences that comprise
episodic memory. Dentate gyrus granule cells receive highly-processed sensory information …

Hippocampal neurogenesis promotes effortful responding but does not regulate effort‐based choice

DR Seib, O PrinczLebel, ER Chahley… - …, 2022 - Wiley Online Library
A fundamental trait of depression is low motivation. Hippocampal neurogenesis has been
associated with motivational deficits but detailed evidence on how it regulates human‐relevant …

Correction: Intact memory for local and distal cues in male and female rats that lack adult neurogenesis

DR Seib, E Chahley, O Princz-Lebel, JS Snyder - Plos one, 2018 - journals.plos.org
There is an error in reference 25. The correct reference is: Yagi S, Chow C, Lieblich SE,
Galea LA. Sex and strategy use matters for pattern separation, adult neurogenesis, and …

Optimization of the touchscreen-based visuomotor conditional learning task in mice

O Princz-Lebel, DI Wasserman, M Skirzewski… - 2019 - ir.lib.uwo.ca
The translational gap between animal models and clinical trials is a longstanding, yet
largely unresolved, limitation in the study of cognition. This discrepancy is largely due to the …

Investigating Humor Processing in Parkinson's Disease

MTM Prenger - 2020 - search.proquest.com
… Erind Alushaj, Madeline Gilchrist, and Oren Princz-Lebel. You have made my experience
as … Charles, Olivia Ghosh-Swaby, and Oren Princz-Lebel. You are the best group of friends I …