Biomarkers of traumatic brain injury: temporal changes in body fluids

H Adrian, K Mårten, N Salla, V Lasse - Eneuro, 2016 - eneuro.org
Traumatic brain injuries (TBIs) are caused by a hit to the head or a sudden acceleration/deceleration
movement of the head. Mild TBIs (mTBIs) and concussions are difficult to diagnose. …

[HTML][HTML] Vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic stress

…, S Ruohonen, ST Ruohonen, S Nuutinen… - Scientific reports, 2019 - nature.com
The intermediate filament (IF) cytoskeleton has been proposed to regulate morphogenic
processes by integrating the cell fate signaling machinery with mechanical cues. Signaling …

Evaluation of the effect of fingolimod treatment on microglial activation using serial PET imaging in multiple sclerosis

…, E Rissanen, J Tuisku, S Nuutinen… - Journal of Nuclear …, 2017 - Soc Nuclear Med
Traditionally, multiple sclerosis (MS) has been considered a white matter disease with focal
inflammatory lesions. It is, however, becoming clear that significant pathology, such as …

Melanocortin 1 receptor signaling regulates cholesterol transport in macrophages

P Rinne, M Rami, S Nuutinen, D Santovito… - Circulation, 2017 - Am Heart Assoc
Background: The melanocortin 1 receptor (MC1-R) is expressed by monocytes and
macrophages, where it exerts anti-inflammatory actions on stimulation with its natural ligand α-…

Pharmacological activation of the melanocortin system limits plaque inflammation and ameliorates vascular dysfunction in atherosclerotic mice

…, H Salomäki, E Koskinen, S Nuutinen… - … , and vascular biology, 2014 - Am Heart Assoc
Objective— Melanocortin peptides have been shown to elicit anti-inflammatory actions and
to promote vascular endothelial function by activating type 1 and 3 melanocortin receptors. …

Melanocortin 1 Receptor Deficiency Promotes Atherosclerosis in Apolipoprotein E−/− Mice

…, JJ Kadiri, M Velasco-Delgado, S Nuutinen… - … and Vascular Biology, 2018 - Am Heart Assoc
Objective— The MC1-R (melanocortin 1 receptor) is expressed by monocytes and macrophages
where it mediates anti-inflammatory actions. MC1-R also protects against macrophage …

Deficiency in melanocortin 1 receptor signaling predisposes to vascular endothelial dysfunction and increased arterial stiffness in mice and humans

P Rinne, A Ahola-Olli, S Nuutinen… - … , and vascular biology, 2015 - Am Heart Assoc
Objective— The melanocortin 1 receptor (MC1-R) is expressed by vascular endothelial
cells and shown to enhance nitric oxide (NO) availability and vasodilator function on …

[HTML][HTML] Melanocortin overexpression limits diet-induced inflammation and atherosclerosis in LDLR−/− mice

S Nuutinen, L Ailanen, E Savontaus… - Journal of …, 2018 - joe.bioscientifica.com
Atherosclerosis is a chronic inflammatory disease of the arteries. The disease is initiated by
endothelial dysfunction that allows the transport of leukocytes and low-density lipoprotein …

[PDF][PDF] Lapset oman oppimisympäristön suunnittelijoina päiväkodissa

S Nuutinen - 2019 - erepo.uef.fi
Too often, the involvement of children is overshadowed by the biggest decisions, because
they are still perceived as underdeveloped in making opinions or making decisions. However, …

Natriumin aineenvaihdunta ja dysnatremiat naudoilla

S Nuutinen - 2021 - helda.helsinki.fi
Tämän kirjallisuuskatsauksen tavoitteena on tarkastella natriumin tarpeellisuutta naudoille ja
kartoittaa häiriöitä, joita dysnatremiat voivat saada aikaan. Dysnatremia tarkoittaa natriumin …