Neural stem cell (NSC) transplantation can influence immune responses and suppress
inflammation in the CNS. Metabolites, such as succinate, modulate the phenotype and function of …

Neural stem cell (NSC) transplantation induces recovery in animal models of central nervous
system (CNS) diseases. Although the replacement of lost endogenous cells was originally …

Ozone therapy has been widely used in everyday clinical practice over the last few years,
leading to significant clinical results in the treatment of herniated discs and pain management. …

Adult stem cells are fundamental to maintain tissue homeostasis, growth, and regeneration.
They reside in specialized environments called niches. Following activating signals, they …

Ischemic stroke continues to be a leading cause of morbidity and mortality throughout the
world. To protect and/or repair the ischemic brain, a multitiered approach may be centered on …

In 2021 the World Health Organization published the fifth and latest version of the Central
Nervous System tumors classification, which incorporates and summarizes a long list of …

Neurodegenerative disorders are characterized by the progressive loss of central and/or
peripheral nervous system neurons. Within this context, neuroinflammation comes up as one of …

Simple Summary The biological pathways underlying glioblastoma malignancy and radioresistance
are still unclear. In this review, we describe the role of the hypoxic microenvironment …

Mesenchymal stromal cells (MSCs) within the protective microenvironment of multiple
myeloma (MM) promote tumor growth, confer chemoresistance and support metabolic needs of …

The proteasome inhibitor bortezomib (BTZ) has emerged as an effective drug for the treatment
of multiple myeloma even though many patients relapse from BTZ therapy. The present …