Synaptic transmission constitutes the primary mode of communication between neurons. It
is extensively studied in rodent but not human neocortex. We characterized synaptic …

Current knowledge of thalamocortical interaction comes mainly from studying lemniscal
thalamic systems. Less is known about paralemniscal thalamic nuclei function. In the vibrissae …

Neocortical cholinergic activity plays a fundamental role in sensory processing and
cognitive functions. Previous results have suggested a refined anatomical and functional …

… Using this approach, we estimated N RRP to be between two to three for synaptic connections
between L5_TTPCs. To constrain N RRP values for other connections in the microcircuit, …

In recent years, large-scale computational models of the cortex have emerged as a powerful
way to study the multi-scale mechanisms of neural processing. However, due to …

Sensory experience has a profound effect on neocortical neurons. Passive stimulation of
whiskers or sensory deprivation from whiskers can induce long-lasting changes in neuronal …

… Figure Contributions: Natali Barros-Zulaica performed the experiments. All authors … Figure
Contributions: Natali Barros-Zulaica performed the experiments. All authors analyzed the data. …

The organizational principles that distinguish the human brain from other species have been
a long-standing enigma in neuroscience. Focusing on the uniquely evolved cortical layers …

The term synaptic plasticity implies modification in the strength or efficacy of synaptic
transmission between pre-existing synapses. Long-term changes in synaptic efficacy have been …

… (B) Superimposed averaged EPSP and EPSP-Ca 2+ spike (n = 20 as in all other Figures) …
N. Barros-Zulaica was a doctoral fellow funded by the BFU2012-36107 grant. We thank …