User profiles for Mikaela A. Laine
Mikaela A LaineLecturer in Neuroscience and Psychology Verified email at smith.edu Cited by 420 |
[HTML][HTML] Brain activation induced by chronic psychosocial stress in mice
MA Laine, E Sokolowska, M Dudek, SA Callan… - Scientific reports, 2017 - nature.com
Chronic psychosocial stress is a well-established risk factor for neuropsychiatric diseases.
Abnormalities in brain activity have been demonstrated in patients with stress-related …
Abnormalities in brain activity have been demonstrated in patients with stress-related …
Genetic control of myelin plasticity after chronic psychosocial stress
MA Laine, K Trontti, Z Misiewicz, E Sokolowska… - eneuro, 2018 - eneuro.org
Anxiety disorders often manifest in genetically susceptible individuals after psychosocial
stress, but the mechanisms underlying these gene-environment interactions are largely …
stress, but the mechanisms underlying these gene-environment interactions are largely …
[HTML][HTML] Multi-omics analysis identifies mitochondrial pathways associated with anxiety-related behavior
Stressful life events are major environmental risk factors for anxiety disorders, although not
all individuals exposed to stress develop clinical anxiety. The molecular mechanisms …
all individuals exposed to stress develop clinical anxiety. The molecular mechanisms …
Darting across space and time: parametric modulators of sex-biased conditioned fear responses
…, M Fanikos, E Golden, MA Laine… - Learning & …, 2022 - learnmem.cshlp.org
Pavlovian fear conditioning is a widely used behavioral paradigm for studying associative
learning in rodents. Despite early recognition that subjects may engage in a variety of both …
learning in rodents. Despite early recognition that subjects may engage in a variety of both …
Sounding the alarm: sex differences in rat ultrasonic vocalizations during Pavlovian fear conditioning and extinction
MA Laine, JR Mitchell, J Rhyner, R Clark, A Kannan… - ENeuro, 2022 - eneuro.org
Pavlovian fear conditioning is a prevalent tool in the study of aversive learning, which is a
key component of stress-related psychiatric disorders. Adult rats can exhibit various threat-…
key component of stress-related psychiatric disorders. Adult rats can exhibit various threat-…
[HTML][HTML] CB1R blockade unmasks TRPV1-mediated contextual fear generalization in female, but not male rats
Increasing evidence suggests that the neurobiological processes that govern learning and
memory can be different in males and females, but many of the specific mechanisms …
memory can be different in males and females, but many of the specific mechanisms …
Genetic variants associated with anxiety and stress-related disorders: a genome-wide association study and mouse-model study
Importance Anxiety and stress-related disorders are among the most common mental
disorders. Although family and twin studies indicate that both genetic and environmental factors …
disorders. Although family and twin studies indicate that both genetic and environmental factors …
[HTML][HTML] Node of Ranvier remodeling in chronic psychosocial stress and anxiety
MK Koskinen, M Laine, A Abdollahzadeh… - …, 2023 - nature.com
Differential expression of myelin-related genes and changes in myelin thickness have been
demonstrated in mice after chronic psychosocial stress, a risk factor for anxiety disorders. To …
demonstrated in mice after chronic psychosocial stress, a risk factor for anxiety disorders. To …
Genome-wide association study of anxiety and stress-related disorders in the iPSYCH cohort
Anxiety and stress-related disorders (ASRD) are among the most common mental disorders
with the majority of patients suffering from additional disorders. Family and twin studies …
with the majority of patients suffering from additional disorders. Family and twin studies …
Gene-environment interaction in myelin plasticity after chronic psychosocial stress
MA Laine, K Trontti, Z Misiewicz, E Sokolowska… - European …, 2019 - ecnp.eu
Background Mikaela A Laine1, Kalevi Trontti1, Zuzanna Misiewicz1, Ewa Sokolowska1,
Eva Rikandi2, 3, 4, Natalia Kulesskaya1, Aino Heikkinen1, Suvi Saarnio1, Ingrid Balcells1, …
Eva Rikandi2, 3, 4, Natalia Kulesskaya1, Aino Heikkinen1, Suvi Saarnio1, Ingrid Balcells1, …