… Levine… Formaldehyde regulates S-adenosylmethionine biosynthesis and one-carbon
metabolism … Looters continue to pillage Afghanistan’s rich archaeological heritage …

A repetitive DNA sequence has been identified in the Drosophila melanogaster genome
that appears to be localized specifically within genes of the bithorax and Antennapedia …

The US National Institute of Neurological Disorders and Stroke convened major stakeholders
in June 2012 to discuss how to improve the methodological reporting of animal studies in …

Loss-of-function mutations in parkin are the major cause of early-onset familial Parkinson's
disease. To investigate the pathogenic mechanism by which loss of parkin function causes …

To elucidate the pathogenic mechanisms in Huntington's disease (HD) elicited by expression
of full-length human mutant huntingtin (fl-mhtt), a bacterial artificial chromosome (BAC)-…

Inactivation of the mouse homologue of the Huntington disease gene (Hdh) results in early
embryonic lethality. To investigate the normal function of Hdh in the adult and to evaluate …

Accumulation of α-synuclein in brain is a hallmark of synucleinopathies, neurodegenerative
diseases that include Parkinson's disease. Mice overexpressing α-synuclein under the Thy-…

Recent findings on the clinical, electroencephalography (EEG), neuroimaging, and surgical
outcomes are reviewed comparing patients with Palmini type I (mild) and type II (severe) …

Alterations in the corticostriatal pathway may precede symptomatology and striatal cell death
in Huntington's disease (HD) patients. Here we examined spontaneous EPSCs in striatal …

Dopamine input to the striatum is required for voluntary motor movement, behavioral reinforcement,
and responses to drugs of abuse. It is speculated that these functions are dependent …