Mouse models of Streptozotocin (STZ) induced diabetes represent the most widely used
preclinical diabetes research systems. We applied state of the art optical imaging schemes, …

The possibility to quantitatively study specific molecular/cellular features of complete human
organs with preserved spatial 3D context would have widespread implications for pre-…

The possibility to assess pancreatic anatomy with microscopic resolution in three dimensions
(3D) would significantly add to pathological analyses of disease processes. Pancreatic …

Opsin 3 (Opn3) is highly expressed in the adult brain, however, information for spatial and
temporal expression patterns during embryogenesis is significantly lacking. Here, an Opn3-…

In the group testing problem, which goes back to the work of Dorfman (1943), we aim to
identify a small set of $ k\sim n^\theta $ infected individuals out of a population size $ n $, $0<\…

Objective Early postnatal life is a critical period for the establishment of the functional β-cell
mass that will sustain whole-body glucose homeostasis during the lifetime. β cells are formed …

In the group testing problem we aim to identify a small number of infected individuals within
a large population. We avail ourselves to a procedure that can test a group of multiple …

We study the group testing problem where the goal is to identify a set of k infected individuals
carrying a rare disease within a population of size n, based on the outcomes of pooled …

Introduction Optical Projection Tomography (OPT) and light sheet fluorescence microscopy (LSFM)
are high resolution optical imaging techniques, ideally suited for ex vivo 3D whole …

Viral tropism within the brain and the role(s) of vertebrate immune response to neurotropic
flaviviruses infection is largely understudied. We combine multimodal imaging (cm-nm scale) …