User profiles for Matt S. Ramer

Matt S Ramer

British Columbia Neurotrauma Fund Professor
Verified email at icord.org
Cited by 7719

[HTML][HTML] Wallerian degeneration: gaining perspective on inflammatory events after peripheral nerve injury

AD Gaudet, PG Popovich, MS Ramer - Journal of neuroinflammation, 2011 - Springer
In this review, we first provide a brief historical perspective, discussing how peripheral nerve
injury (PNI) may have caused World War I. We then consider the initiation, progression, and …

Functional regeneration of sensory axons into the adult spinal cord

MS Ramer, JV Priestley, SB McMahon - Nature, 2000 - nature.com
The arrest of dorsal root axonal regeneration at the transitional zone between the peripheral
and central nervous system has been repeatedly described since the early twentieth …

Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury

…, CB McBride, JD Steeves, MS Ramer… - Journal of …, 2004 - Soc Neuroscience
Minocycline has been demonstrated to be neuroprotective after spinal cord injury (SCI).
However, the cellular consequences of minocycline treatment on the secondary injury response …

Restoring function after spinal cord injury: towards clinical translation of experimental strategies

LM Ramer, MS Ramer, EJ Bradbury - The Lancet Neurology, 2014 - thelancet.com
Spinal cord injury is currently incurable and treatment is limited to minimising secondary
complications and maximising residual function by rehabilitation. Improved understanding of the …

Spinal nerve lesion-induced mechanoallodynia and adrenergic sprouting in sensory ganglia are attenuated in interleukin-6 knockout mice

MS Ramer, PG Murphy, PM Richardson, MA Bisby - Pain, 1998 - Elsevier
Tight ligation and transection of the L5 spinal nerve (SNL) gives rise to pain which is
dependent upon activity in the sympathetic nervous system. It also results in novel adrenergic …

Wallerian degeneration is required for both neuropathic pain and sympathetic sprouting into the DRG

MS Ramer, GD French, MA Bisby - Pain, 1997 - Elsevier
Chronic loose constriction of the sciatic nerve produces mechanoallodynia and thermal
hyperalgesia in rats and mice, and the behaviour develops during the time in which the nerve …

Causes and consequences of sympathetic basket formation in dorsal root ganglia

MS Ramer, SWN Thompson, SB McMahon - Pain, 1999 - Elsevier
Injury to peripheral nerves can result in severe and intractable neuropathic pain, and in some
cases the symptoms are sympathetically maintained. In recent years much effort has been …

Nerve growth factor induces P2X3 expression in sensory neurons

MS Ramer, EJ Bradbury… - Journal of …, 2001 - Wiley Online Library
Glial cell line‐derived neurotrophic factor (GDNF) and nerve growth factor (NGF) are
neuroprotective for subpopulations of sensory neurons and thus are candidates for pain treatment. …

[HTML][HTML] Small-group learning in an upper-level university biology class enhances academic performance and student attitudes toward group work

…, LM Ramer, J Nakonechny, JJ Cragg, MS Ramer - PloS one, 2010 - journals.plos.org
To improve science learning, science educators' teaching tools need to address two major
criteria: teaching practice should mirror our current understanding of the learning process; …

Rapid sprouting of sympathetic axons in dorsal root ganglia of rats with a chronic constriction injury

MS Ramer, MA Bisby - Pain, 1997 - Elsevier
We compared the time-course of sympathetic nerve sprouting into the L4–6 dorsal root ganglia
(DRG) of adult rats following a chronic constriction injury (CCI) made on the sciatic nerve, …