Exposure to early-life adversity may program brain function to prepare individuals for
adaptation to matching environmental contexts. In this study we tested this hypothesis in more …

Early life adversity is a well-known risk factor for behavioral dysfunction later in life, including
the formation of contextual memory; it is also (transiently) accompanied by hyperactivity of …

Corticosterone facilitates behavioral adaptation to a novel experience in a coordinate
manner via mineralocorticoid (MR) and glucocorticoid receptors (GR). Initially, MR mediates …

Social interaction with unknown individuals requires fast processing of information to decide
whether it is friend or foe. This process of discrimination and decision-making is stressful …

The early postnatal period is a highly sensitive time period for the developing brain, both in
humans and rodents. During this time window, exposure to adverse experiences can …

Early life adversity can have long-lasting impact on learning and memory processes and
increase the risk to develop stress-related psychopathologies later in life. In this study we …

Adrenal corticosteroid hormones act via mineralocorticoid (MR) and glucocorticoid receptors
(GR) in the brain, influencing learning and memory. MRs have been implicated in the initial …

Mineralocorticoid receptors (MRs) have been implicated in behavioral adaptation and learning
and memory. Since—at least in humans—MR function seems to be sex-dependent, we …

… of neurons in the basolateral amygdala (Pillai et al., unpublished observations) and to alter
– although less strikingly - dendritic arborizationin the dorsomedial striatum in mice (Arp et al.…

… We are grateful to Marcel Schaaf (IBL) for providing the pRSET-b-mCherry plasmid, and
Hans den Dulk and Marit Arp (LIC) for technical support. This work was supported by a grant …