User profiles for Marian Joëls

Marian Joels

University Medical Center Utrecht
Verified email at umcutrecht.nl
Cited by 50904

Stress and the brain: from adaptation to disease

ER De Kloet, M Joëls, F Holsboer - Nature reviews neuroscience, 2005 - nature.com
In response to stress, the brain activates several neuropeptide-secreting systems. This eventually
leads to the release of adrenal corticosteroid hormones, which subsequently feed back …

The neuro-symphony of stress

M Joëls, TZ Baram - Nature reviews neuroscience, 2009 - nature.com
The impact of stress on brain function is increasingly recognized. Various substances are
released in response to stress and can influence distinct neuronal circuits, but the functional …

Learning under stress: how does it work?

M Joëls, Z Pu, O Wiegert, MS Oitzl… - Trends in cognitive …, 2006 - cell.com
The effects of stress on learning and memory are not always clear: both facilitating and
impairing influences are described in the literature. Here we propose a unifying theory, which …

Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy

…, GM Goodwin, P Gorwood, TM Jay, M Joëls… - Nature reviews Drug …, 2012 - nature.com
Studies of psychiatric disorders have traditionally focused on emotional symptoms such as
depression, anxiety and hallucinations. However, poorly controlled cognitive deficits are …

Dynamic adaptation of large-scale brain networks in response to acute stressors

EJ Hermans, MJAG Henckens, M Joëls… - Trends in …, 2014 - cell.com
Stress initiates an intricate response that affects diverse cognitive and affective domains, with
the goal of improving survival chances in the light of changing environmental challenges. …

Stress effects on memory: an update and integration

L Schwabe, M Joëls, B Roozendaal, OT Wolf… - Neuroscience & …, 2012 - Elsevier
It is well known that stressful experiences may affect learning and memory processes. Less
clear is the exact nature of these stress effects on memory: both enhancing and impairing …

Brain corticosteroid receptor balance in health and disease

…, E Vreugdenhil, MS Oitzl, M Joëls - Endocrine …, 1998 - academic.oup.com
Marian Joëls Marian Joëls … Oitzl, Marian Joëls, Brain Corticosteroid Receptor
Balance in Health and Disease, Endocrine Reviews, Volume 19, Issue 3, 1 June 1998 …

Stress and cognition: are corticosteroids good or bad guys?

ER De Kloet, MS Oitzl, M Joëls - Trends in neurosciences, 1999 - cell.com
Corticosteroid hormones secreted by the adrenal cortex protect the brain against adverse
events and are essential for cognitive performance. However, in recent literature, the central …

Mineralocorticoid receptors are indispensable for nongenomic modulation of hippocampal glutamate transmission by corticosterone

…, F Tronche, G Schütz, M Joëls - Proceedings of the …, 2005 - National Acad Sciences
The adrenal hormone corticosterone transcriptionally regulates responsive genes in the
rodent hippocampus through nuclear mineralocorticoid and glucocorticoid receptors. Via this …

Maternal care and hippocampal plasticity: evidence for experience-dependent structural plasticity, altered synaptic functioning, and differential responsiveness to …

…, MJ Meaney, ER De Kloet, M Joëls… - Journal of …, 2008 - Soc Neuroscience
Maternal licking and grooming (LG) in infancy influences stress responsiveness and cognitive
performance in the offspring. We examined the effects of variation in the frequency of pup …