Skin cancer has become the most common neoplasm in the United States. With early diagnosis
and appropriate management, most skin cancers have an overall 5-year survival rate of …

SLP76 and SLP65 are adaptor proteins that lack intrinsic enzymatic activity but contain
multiple protein-binding domains. These proteins are essential for signalling downstream of …

Cilia are organelles that project from most eukaryotic organisms and cell types. Their
pervasiveness stems from having remarkably versatile propulsive and sensory functions, which in …

Defective brain insulin signaling has been suggested to contribute to the cognitive deficits in
patients with Alzheimer’s disease (AD). Although a connection between AD and diabetes …

To assess whether selective microtubule-based vesicle transport underlies the polarized
distribution of neuronal proteins, we expressed green fluorescent protein– (GFP-) tagged …

Enteric pathogens are exposed to a dynamic polymicrobial environment in the gastrointestinal
tract 1 . This microbial community has been shown to be important during infection, but …

Disruption of axonal transport is a hallmark of several neurodegenerative diseases,
including Alzheimer's disease (AD). Even though defective transport is considered an early …

OBJECTIVES Little is known about the prescribing of medications in the growing population
of homebound older adults. We report on the prevalence and pattern of inappropriate …

… We thank members of the Henrickson and Silverman laboratories for helpful discussions.
We thank the staff at the mouse facility at Biomedical Research Building at the University of …

Dense-core vesicles (DCVs) are responsible for transporting, processing, and secreting
neuropeptide cargos that mediate a wide range of biological processes, including neuronal …