Stressful events promote neurochemical changes that may be involved in the provocation of
depressive disorder. In addition to neuroendocrine substrates (eg corticotropin releasing …

Cytokines whose primary function is that of acting as signaling molecules of the immune
system, have been implicated in the provocation or exacerbation of mood disorders such as …

… Recent research by Poulter’s group supports the role of alterations to the GABAergic
interneuron network in the piriform cortex after kindling-induced seizures.Immunohistochemistry …

Corticotropin-releasing hormone (CRH) and GABA have been implicated in depression,
and there is reason to believe that GABA may influence CRH functioning. The levels of CRH, …

BACKGROUND: Epigenetic mechanisms may be involved in the reprogramming of gene
expression in response to stressful stimuli. This investigation determined whether epigenetic …

Stress and anxiety disorders are risk factors for depression and these behaviors are modulated
by corticotrophin-releasing factor receptor 1 (CRFR1) and serotonin receptor (5-HT 2 R). …

The expression of mRNAs coding for alpha 1, alpha 2, alpha 3, alpha 5, and alpha 6 subunits
of the GABAA neurotransmitter receptor was followed during the development of the rat …

… cut into 6 major pieces (4 cortical lobes, basal ganglia–diencephalon and lower brain
stem–cerebellum), rapidly frozen on dry ice and stored at −70C until microdissection (2 d–2 mo …

A brief review of kindling is provided, which highlights some important points of historical
interest often overlooked by researchers. These points include the fact that the original rating …

Oxidative stress has been implicated as a key trigger of neuronal apoptosis in stroke and
neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease and …