User profiles for Leonardo Belluscio

Leonardo Belluscio

NIH
Verified email at nih.gov
Cited by 10184

Neurotrophin-3: a neurotrophic factor related to NGF and BDNF

PC Maisonpierre, L Belluscio, S Squinto, NY Ip… - Science, 1990 - science.org
The development and maintenance of the nervous system depends on proteins known as
neurotrophic factors. Although the prototypical neurotrophic factor, nerve growth factor (NGF), …

NT-3, BDNF, and NGF in the developing rat nervous system: parallel as well as reciprocal patterns of expression

PC Maisonpierre, L Belluscio, B Friedman… - Neuron, 1990 - cell.com
To obtain insight into the site and stage specificity of nerve growth factor (NGF), brain-derived
neurotrophic factor (BDNF), and neurotrophin3(NT-31 action in vivo, we compared the …

Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution, and receptor specificity.

…, PF Jones, DR Gies, L Belluscio… - Proceedings of the …, 1992 - National Acad Sciences
Nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 (NT-3) are the
three members of the neurotrophin family known to exist in mammals. Recently, a fourth …

[PDF][PDF] Mice deficient in Golf are anosmic

L Belluscio, GH Gold, A Nemes, R Axel - Neuron, 1998 - cell.com
We have used gene targeting to examine the role of the Gα subunit, G olf , in olfactory signal
transduction. Mice homozygous for a null mutation in G olf show a striking reduction in the …

Human and rat brain-derived neurotrophic factor and neurotrophin-3: gene structures, distributions, and chromosomal localizations

…, MM Le Beau, R Espinosa III, NY Ip, L Belluscio… - Genomics, 1991 - Elsevier
The development and maintenance of the vertebrate nervous system depends upon neuronal
survival proteins known as neurotrophic factors. Nerve growth factor (NGF) remains the …

[HTML][HTML] A map of pheromone receptor activation in the mammalian brain

L Belluscio, G Koentges, R Axel, C Dulac - Cell, 1999 - cell.com
In mammals, the detection of pheromones is mediated by the vomeronasal system. We have
employed gene targeting to visualize the pattern of projections of axons from vomeronasal …

[PDF][PDF] Golfα mediates dopamine D1 receptor signaling

X Zhuang, L Belluscio, R Hen - The Journal of Neuroscience, 2000 - Soc Neuroscience
SKF-81297 or the psychostimulant cocaine. Moreover, Golfα knockout mice did not display
cocaine-induced c-fos expression in the striatum. Finally, in the absence of Golfα, striatal D1 …

Symmetry, stereotypy, and topography of odorant representations in mouse olfactory bulbs

L Belluscio, LC Katz - Journal of Neuroscience, 2001 - Soc Neuroscience
The molecular basis of vertebrate odorant representations has been derived extensively from
mice. The functional correlates of these molecular features were visualized using optical …

Functional reactivity of cerebral capillaries

…, V Schram, JT Russell, L Belluscio… - Journal of Cerebral …, 2008 - journals.sagepub.com
The spatiotemporal evolution of cerebral microcirculatory adjustments to functional brain
stimulation is the fundamental determinant of the functional specificity of hemodynamically …

Odorant receptors instruct functional circuitry in the mouse olfactory bulb

L Belluscio, C Lodovichi, P Feinstein, P Mombaerts… - Nature, 2002 - nature.com
The mammalian olfactory system detects and discriminates thousands of odorants using
many different receptors expressed by sensory neurons in the nasal epithelium 1 . Axonal …