[HTML][HTML] Gesicle-mediated delivery of CRISPR/Cas9 ribonucleoprotein complex for inactivating the HIV provirus
LA Campbell, LM Coke, CT Richie, LV Fortuno… - Molecular Therapy, 2019 - cell.com
Investigators have utilized the CRISPR/Cas9 gene-editing system to specifically target well-conserved
regions of HIV, leading to decreased infectivity and pathogenesis in vitro and ex …
regions of HIV, leading to decreased infectivity and pathogenesis in vitro and ex …
[PDF][PDF] Neuron-specific genome modification in the adult rat brain using CRISPR-Cas9 transgenic rats
Historically, the rat has been the preferred animal model for behavioral studies. Limitations
in genome modification have, however, caused a lag in their use compared to the bevy of …
in genome modification have, however, caused a lag in their use compared to the bevy of …
Effects of withdrawal from cocaine self-administration on rat orbitofrontal cortex parvalbumin neurons expressing cre recombinase: sex-dependent changes in …
The orbitofrontal cortex (OFC) is a brain region involved in higher-order decision-making.
Rodent studies show that cocaine self-administration (CSA) reduces OFC contribution to goal-…
Rodent studies show that cocaine self-administration (CSA) reduces OFC contribution to goal-…
In vitro modeling of HIV proviral activity in microglia
…, CT Richie, Y Zhang, EJ Heathward, LM Coke… - The FEBS …, 2017 - Wiley Online Library
Microglia, the resident macrophages of the brain, play a key role in the pathogenesis of HIV
‐associated neurocognitive disorders ( HAND ) due to their productive infection by HIV . This …
‐associated neurocognitive disorders ( HAND ) due to their productive infection by HIV . This …
Thermodynamic aspects of the heterogeneous deacetylation of β-chitin: Reaction mechanisms
G Lamarque, G Chaussard, A Domard - Biomacromolecules, 2007 - ACS Publications
… that the transformation of soda hydrates as the deacetylation … /soda/water/sodium acetate
was the angle stone of complex equilibriums governing the reaction, and we propose soda …
was the angle stone of complex equilibriums governing the reaction, and we propose soda …
Myocarditis and brain abscess caused by disseminated Scedosporium boydii infection
DL Jackson, L Coke, SX Zhang, C Steenbergen… - Journal of the National …, 2024 - Elsevier
Scedosporium spp. is a fungal species documented as the cause of infections involving the
lungs, brain, and other organ systems in both immunocompetent and immunocompromised …
lungs, brain, and other organ systems in both immunocompetent and immunocompromised …
[HTML][HTML] Invasive Candida pneumonia, in association with Candida esophagitis and gastritis, in a presumably immunocompetent patient
D Jackson, L Coke, K Fernandez… - Autopsy and Case …, 2023 - SciELO Brasil
Candida pneumonia remains a difficult diagnosis and is most common in immunocompromised
individuals. It has been rarely reported in immunocompetent individuals. We present a …
individuals. It has been rarely reported in immunocompetent individuals. We present a …
[PDF][PDF] Undiagnosed Metastatic Breast Carcinoma Presenting as Thrombotic Thrombocytopenic Purpura
DL Jackson, L Coke, O Oni, L Taddesse-Heath… - Cureus, 2023 - cureus.com
Cancer-associated thrombotic microangiopathy has a documented relationship with
metastatic disease. Other examples of thrombotic microangiopathy (TMA) include thrombotic …
metastatic disease. Other examples of thrombotic microangiopathy (TMA) include thrombotic …
[PDF][PDF] Modification of hydroxamic acid containing compounds for improved metal chelation
K Arora, L Coke, E Benjamin III, E Benjamin - 2016 - pdfs.semanticscholar.org
Hydroxamic acids (HXA) are functional groups with the ability to strongly chelate metal ions
found in the reaction centers of biologically important proteins including that of Tumor …
found in the reaction centers of biologically important proteins including that of Tumor …
New route of deacetylation of α-and β-chitins by means of freeze− pump out− thaw cycles
G Lamarque, M Cretenet, C Viton… - Biomacromolecules, 2005 - ACS Publications
… Roberts 47 stated that washing steps between two successive reactions could either
eliminate poor reactive chitin/sodium hydrate complexes or decrease the soda concentration …
eliminate poor reactive chitin/sodium hydrate complexes or decrease the soda concentration …