[PDF][PDF] The GTPase dMiro is required for axonal transport of mitochondria to Drosophila synapses
…, L Marin, MP Charlton, HL Atwood, KE Zinsmaier - Neuron, 2005 - cell.com
We have identified EMS-induced mutations in Drosophila Miro (dMiro), an atypical
mitochondrial GTPase that is orthologous to human Miro (hMiro). Mutant dmiro animals exhibit …
mitochondrial GTPase that is orthologous to human Miro (hMiro). Mutant dmiro animals exhibit …
Paralysis and Early Death in Cysteine String Protein Mutants of Drosophila
KE Zinsmaier, KK Eberle, E Buchner, N Walter… - Science, 1994 - science.org
Multimeric complexes of synaptic vesicle and terminal membrane proteins are important
components of the neurotransmitter release mechanism. The csp gene of Drosophila encodes …
components of the neurotransmitter release mechanism. The csp gene of Drosophila encodes …
Membrane potential modulates plasma membrane phospholipid dynamics and K-Ras signaling
Plasma membrane depolarization can trigger cell proliferation, but how membrane potential
influences mitogenic signaling is uncertain. Here, we show that plasma membrane …
influences mitogenic signaling is uncertain. Here, we show that plasma membrane …
Drosophila Miro is required for both anterograde and retrograde axonal mitochondrial transport
…, F Hu, S Panchumarthi, KE Zinsmaier - Journal of …, 2009 - Soc Neuroscience
Microtubule-based transport of mitochondria into dendrites and axons is vital for sustaining
neuronal function. Transport along microtubule tracks proceeds in a series of plus and minus …
neuronal function. Transport along microtubule tracks proceeds in a series of plus and minus …
A Cysteine-String Protein is Expressed in Retina and Brain of Drosophila
KE Zinsmaier, A Hofbauer, G Heimbeck… - Journal of …, 1990 - Taylor & Francis
Antibodies can be used to identify tissue- and stage-specifically expressed genes. A
monoclonal antibody MAB ab49 from a hybridoma library screened for immunohistochemical …
monoclonal antibody MAB ab49 from a hybridoma library screened for immunohistochemical …
Presynaptic dysfunction in Drosophila csp mutants
JA Umbach, KE Zinsmaier, KK Eberle, E Buchner… - Neuron, 1994 - cell.com
Cysteine string proteins are synapse-specific proteins. In Drosophila, csp deletion mutants
exhibit temperature-sensitive paralysis and early death. Here, we report that neuromuscular …
exhibit temperature-sensitive paralysis and early death. Here, we report that neuromuscular …
[PDF][PDF] Drosophila Hsc70-4 is critical for neurotransmitter exocytosis in vivo
Previous in vitro studies of cysteine-string protein (CSP) imply a potential role for the clathrin-uncoating
ATPase Hsc70 in exocytosis. We show that hypomorphic mutations in Drosophila …
ATPase Hsc70 in exocytosis. We show that hypomorphic mutations in Drosophila …
Miro's N-terminal GTPase domain is required for transport of mitochondria into axons and dendrites
…, RM Sangston, M Gonzalez, KE Zinsmaier - Journal of …, 2015 - Soc Neuroscience
Mitochondria are dynamically transported in and out of neuronal processes to maintain
neuronal excitability and synaptic function. In higher eukaryotes, the mitochondrial GTPase Miro …
neuronal excitability and synaptic function. In higher eukaryotes, the mitochondrial GTPase Miro …
Presynaptic mitochondria in functionally different motor neurons exhibit similar affinities for Ca2+ but exert little influence as Ca2+ buffers at nerve firing rates in situ
AK Chouhan, J Zhang, KE Zinsmaier… - Journal of …, 2010 - Soc Neuroscience
Mitochondria accumulate within nerve terminals and support synaptic function, most notably
through ATP production. They can also sequester Ca 2+ during nerve stimulation, but it is …
through ATP production. They can also sequester Ca 2+ during nerve stimulation, but it is …
Overexpression of Cysteine-String Proteins inDrosophila Reveals Interactions with Syntaxin
…, SN Hong, P Bronk, KE Zinsmaier - Journal of …, 1999 - Soc Neuroscience
Cysteine-string proteins (CSPs) are associated with secretory vesicles and critical for regulated
neurotransmitter release and peptide exocytosis. At nerve terminals, CSPs have been …
neurotransmitter release and peptide exocytosis. At nerve terminals, CSPs have been …