User profiles for K. I. Chisholm
Kim ChisholmNeuroscience Researcher, Unicersity of Nottingham Verified email at nottingham.ac.uk Cited by 417 |
[PDF][PDF] Immune or genetic-mediated disruption of CASPR2 causes pain hypersensitivity due to enhanced primary afferent excitability
Human autoantibodies to contactin-associated protein-like 2 (CASPR2) are often associated
with neuropathic pain, and CASPR2 mutations have been linked to autism spectrum …
with neuropathic pain, and CASPR2 mutations have been linked to autism spectrum …
Large scale in vivo recording of sensory neuron activity with GCaMP6
Greater emphasis on the study of intact cellular networks in their physiological environment
has led to rapid advances in intravital imaging of the central nervous system (CNS), while the …
has led to rapid advances in intravital imaging of the central nervous system (CNS), while the …
[HTML][HTML] Encoding of cutaneous stimuli by lamina I projection neurons
KI Chisholm, LL Re, E Polgár, M Gutierrez-Mecinas… - Pain, 2021 - journals.lww.com
Lamina I of the dorsal horn, together with its main output pathway, lamina I projection
neurons, has long been implicated in the processing of nociceptive stimuli, as well as the …
neurons, has long been implicated in the processing of nociceptive stimuli, as well as the …
[HTML][HTML] Cortical mechanisms of single-pulse transcranial magnetic stimulation in migraine
JO Lloyd, KI Chisholm, B Oehle, MG Jones, BN Okine… - …, 2020 - Springer
Single-pulse transcranial magnetic stimulation (sTMS) of the occipital cortex is an effective
migraine treatment. However, its mechanism of action and cortical effects of sTMS in migraine …
migraine treatment. However, its mechanism of action and cortical effects of sTMS in migraine …
[HTML][HTML] The impact of bone cancer on the peripheral encoding of mechanical pressure stimuli
… Author contributions: MW Kucharczyk conceived, designed, and performed all the experiments,
analysed data, and wrote the manuscript; KI Chisholm performed GCaMP experiments …
analysed data, and wrote the manuscript; KI Chisholm performed GCaMP experiments …
Hypothermia protects brain mitochondrial function from hypoxemia in a murine model of sepsis
KI Chisholm, KK Ida, AL Davies… - Journal of Cerebral …, 2016 - journals.sagepub.com
Sepsis is commonly associated with brain dysfunction, but the underlying mechanisms remain
unclear, although mitochondrial dysfunction and microvascular abnormalities have been …
unclear, although mitochondrial dysfunction and microvascular abnormalities have been …
[PDF][PDF] Sodium-calcium exchanger-3 regulates pain “wind-up”: From human psychophysics to spinal mechanisms
Repeated application of noxious stimuli leads to a progressively increased pain perception;
this temporal summation is enhanced in and predictive of clinical pain disorders. Its …
this temporal summation is enhanced in and predictive of clinical pain disorders. Its …
[HTML][HTML] Peripheral inflammatory pain sensitisation is independent of mast cell activation in male mice
The immune and sensory systems are known for their close proximity and interaction. Indeed,
in a variety of pain states, a myriad of different immune cells are activated and recruited, …
in a variety of pain states, a myriad of different immune cells are activated and recruited, …
[HTML][HTML] In vivo imaging of flavoprotein fluorescence during hypoxia reveals the importance of direct arterial oxygen supply to cerebral cortex tissue
KI Chisholm, KK Ida, AL Davies, DB Papkovsky… - Oxygen Transport to …, 2016 - Springer
Live imaging of mitochondrial function is crucial to understand the important role played by
these organelles in a wide range of diseases. The mitochondrial redox potential is a …
these organelles in a wide range of diseases. The mitochondrial redox potential is a …
[HTML][HTML] Protection of cerebral microcirculation, mitochondrial function, and electrocortical activity by small-volume resuscitation with terlipressin in a rat model of …
KK Ida, KI Chisholm, LMS Malbouisson… - British Journal of …, 2018 - Elsevier
Background During early treatment of haemorrhagic shock, cerebral perfusion pressure can
be restored by small-volume resuscitation with vasopressors. Whether this therapy is …
be restored by small-volume resuscitation with vasopressors. Whether this therapy is …