User profiles for K. I. Chisholm

Kim Chisholm

Neuroscience Researcher, Unicersity of Nottingham
Verified email at nottingham.ac.uk
Cited by 417

[PDF][PDF] Immune or genetic-mediated disruption of CASPR2 causes pain hypersensitivity due to enhanced primary afferent excitability

…, GA Weir, SJ Middleton, R Patel, KI Chisholm… - Neuron, 2018 - cell.com
Human autoantibodies to contactin-associated protein-like 2 (CASPR2) are often associated
with neuropathic pain, and CASPR2 mutations have been linked to autism spectrum …

Large scale in vivo recording of sensory neuron activity with GCaMP6

KI Chisholm, N Khovanov, DM Lopes, F La Russa… - eneuro, 2018 - eneuro.org
Greater emphasis on the study of intact cellular networks in their physiological environment
has led to rapid advances in intravital imaging of the central nervous system (CNS), while the …

[HTML][HTML] Encoding of cutaneous stimuli by lamina I projection neurons

KI Chisholm, LL Re, E Polgár, M Gutierrez-Mecinas… - Pain, 2021 - journals.lww.com
Lamina I of the dorsal horn, together with its main output pathway, lamina I projection
neurons, has long been implicated in the processing of nociceptive stimuli, as well as the …

[HTML][HTML] Cortical mechanisms of single-pulse transcranial magnetic stimulation in migraine

JO Lloyd, KI Chisholm, B Oehle, MG Jones, BN Okine… - …, 2020 - Springer
Single-pulse transcranial magnetic stimulation (sTMS) of the occipital cortex is an effective
migraine treatment. However, its mechanism of action and cortical effects of sTMS in migraine …

[HTML][HTML] The impact of bone cancer on the peripheral encoding of mechanical pressure stimuli

MW Kucharczyk, KI Chisholm, F Denk, AH Dickenson… - Pain, 2020 - journals.lww.com
… Author contributions: MW Kucharczyk conceived, designed, and performed all the experiments,
analysed data, and wrote the manuscript; KI Chisholm performed GCaMP experiments …

Hypothermia protects brain mitochondrial function from hypoxemia in a murine model of sepsis

KI Chisholm, KK Ida, AL Davies… - Journal of Cerebral …, 2016 - journals.sagepub.com
Sepsis is commonly associated with brain dysfunction, but the underlying mechanisms remain
unclear, although mitochondrial dysfunction and microvascular abnormalities have been …

[PDF][PDF] Sodium-calcium exchanger-3 regulates pain “wind-up”: From human psychophysics to spinal mechanisms

…, K Adhikari, AB Schmid, R Patel, E Polgár, KI Chisholm… - Neuron, 2022 - cell.com
Repeated application of noxious stimuli leads to a progressively increased pain perception;
this temporal summation is enhanced in and predictive of clinical pain disorders. Its …

[HTML][HTML] Peripheral inflammatory pain sensitisation is independent of mast cell activation in male mice

DM Lopes, F Denk, KI Chisholm, T Suddason… - Pain, 2017 - journals.lww.com
The immune and sensory systems are known for their close proximity and interaction. Indeed,
in a variety of pain states, a myriad of different immune cells are activated and recruited, …

[HTML][HTML] In vivo imaging of flavoprotein fluorescence during hypoxia reveals the importance of direct arterial oxygen supply to cerebral cortex tissue

KI Chisholm, KK Ida, AL Davies, DB Papkovsky… - Oxygen Transport to …, 2016 - Springer
Live imaging of mitochondrial function is crucial to understand the important role played by
these organelles in a wide range of diseases. The mitochondrial redox potential is a …

[HTML][HTML] Protection of cerebral microcirculation, mitochondrial function, and electrocortical activity by small-volume resuscitation with terlipressin in a rat model of …

KK Ida, KI Chisholm, LMS Malbouisson… - British Journal of …, 2018 - Elsevier
Background During early treatment of haemorrhagic shock, cerebral perfusion pressure can
be restored by small-volume resuscitation with vasopressors. Whether this therapy is …