Brief repetitive activation of excitatory synapses in the hippocampus leads to an increase in
synaptic strength that lasts for many hours. This long-term potentiation (LTP) of synaptic …

Addiction is caused, in part, by powerful and long-lasting memories of the drug experience.
Relapse caused by exposure to cues associated with the drug experience is a major clinical …

THE phenomenon of long-term potentiation (LTP), a long lasting increase in the strength of
synaptic transmission which is due to brief, repetitive activation of excitatory afferent fibres, is …

Communication between nerve cells in the central nervous system (CNS) occurs at synapses,
which are specialized sites between the presynaptic nerve terminal and the postsynaptic …

Long-term potentiation (LTP) of synaptic strength, the most established cellular model of
information storage in the brain, is expressed by an increase in the number of postsynaptic …

Learning-related plasticity at excitatory synapses in the mammalian brain requires the
trafficking of AMPA receptors and the growth of dendritic spines. However, the mechanisms that …

tong-term potentiation (LTP) is a long-lasting enhancement of synaptic transmission that can
be induced by brief repetitive stimulation of excitatory pathways in the hippocampus. One of …

TRPV1 receptors have classically been defined as heat-sensitive, ligand-gated, nonselective
cation channels that integrate nociceptive stimuli in sensory neurons. TRPV1 receptors …

The NMDA (N-methyl-D-aspartate) class of glutamate receptor plays a critical role in a
variety of forms of synaptic plasticity in the vertebrate central nervous system 1–5 . One …

Excitatory brain synapses are strengthened or weakened in response to specific patterns of
synaptic activation, and these changes in synaptic strength are thought to underlie persistent …