User profiles for Julian P. Meeks

Julian Meeks

University of Rochester School of Medicine and Dentistry
Verified email at urmc.rochester.edu
Cited by 1371

Action potential initiation and propagation in CA3 pyramidal axons

JP Meeks, S Mennerick - Journal of neurophysiology, 2007 - journals.physiology.org
Thin, unmyelinated axons densely populate the mammalian hippocampus and cortex.
However, the location and dynamics of spike initiation in thin axons remain unclear. We …

Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution

…, H Zhao, R Tomer, R Heintzmann, JP Meeks… - Nature …, 2019 - nature.com
We present cleared-tissue axially swept light-sheet microscopy (ctASLM), which enables
isotropic, subcellular resolution imaging with high optical sectioning capability and a large field …

B cells migrate into remote brain areas and support neurogenesis and functional recovery after focal stroke in mice

…, DM Ramirez, AD Ajay, JP Meeks… - Proceedings of the …, 2020 - National Acad Sciences
Lymphocytes infiltrate the stroke core and penumbra and often exacerbate cellular injury. B
cells, however, are lymphocytes that do not contribute to acute pathology but can support …

Representation and transformation of sensory information in the mouse accessory olfactory system

JP Meeks, HA Arnson, TE Holy - Nature neuroscience, 2010 - nature.com
In mice, nonvolatile social cues are detected and analyzed by the accessory olfactory system
(AOS). Here we provide a first view of information processing in the AOS with respect to …

Selective effects of potassium elevations on glutamate signaling and action potential conduction in hippocampus

JP Meeks, S Mennerick - Journal of Neuroscience, 2004 - Soc Neuroscience
High-frequency synaptic transmission is depressed by moderate rises in the extracellular
potassium concentration ([K + ] o ). Previous reports have indicated that depression of action …

[HTML][HTML] Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors

…, C Miyoshi, Y Irukayama, J Cao, JP Meeks… - Nature …, 2018 - nature.com
Innate behaviors are genetically encoded, but their underlying molecular mechanisms remain
largely unknown. Predator odor 2, 4, 5-trimethyl-3-thiazoline (TMT) and its potent analog 2-…

High threshold, proximal initiation, and slow conduction velocity of action potentials in dentate granule neuron mossy fibers

GJ Kress, MJ Dowling, JP Meeks… - Journal of …, 2008 - journals.physiology.org
Dentate granule neurons give rise to some of the smallest unmyelinated fibers in the
mammalian CNS, the hippocampal mossy fibers. These neurons are also key regulators of …

Action potential fidelity during normal and epileptiform activity in paired soma–axon recordings from rat hippocampus

JP Meeks, X Jiang, S Mennerick - The Journal of physiology, 2005 - Wiley Online Library
Although action potential initiation and propagation are fundamental to nervous system
function, there are few direct electrophysiological observations of propagating action potentials …

Astrocyte membrane responses and potassium accumulation during neuronal activity

JP Meeks, S Mennerick - Hippocampus, 2007 - Wiley Online Library
Older studies suggest that astrocytes act as potassium electrodes and depolarize with the
potassium efflux accompanying neuronal activity. Newer studies suggest that astrocytes …

Functional organization of glomerular maps in the mouse accessory olfactory bulb

GF Hammen, D Turaga, TE Holy, JP Meeks - Nature neuroscience, 2014 - nature.com
The mammalian accessory olfactory system extracts information about species, sex and
individual identity from social odors, but its functional organization remains unclear. We imaged …