Lipid dynamics and peripheral interactions of proteins with membrane surfaces

PKJ Kinnunen, A Kõiv, JYA Lehtonen… - Chemistry and physics …, 1994 - Elsevier
A large body of evidence strongly indicates biomembranes to be organized into compositionally
and functionally specialized domains, supramolecular assemblics, existing on different …

Signaling mechanism of the AT2 angiotensin II receptor: crosstalk between AT1 and AT2 receptors in cell growth

M Horiuchi, JYA Lehtonen, L Daviet - Trends in Endocrinology & …, 1999 - cell.com
The peptide angiotensin (Ang) II exerts a range of actions in the cardiovascular, renal,
reproductive and central nervous systems. At least two distinct Ang II receptor subtypes have been …

BODIL: a molecular modeling environment for structure-function analysis and drug design

JV Lehtonen, DJ Still, V Rantanen, J Ekholm… - Journal of computer …, 2004 - Springer
BODIL is a molecular modeling environment geared to help the user to quickly identify key
features of proteins critical to molecular recognition, especially (1) in drug discovery …

[HTML][HTML] Cloning and characterization of ATRAP, a novel protein that interacts with the angiotensin II type 1 receptor

L Daviet, JYA Lehtonen, K Tamura, DP Griese… - Journal of Biological …, 1999 - ASBMB
The carboxyl-terminal cytoplasmic domain of the angiotensin II type 1 (AT 1 ) receptor has
recently been shown to interact with several classes of cytoplasmic proteins that regulate …

Lipid microdomains in dimyristoylphosphatidylcholine–ceramide liposomes

JM Holopainen, JYA Lehtonen… - Chemistry and physics of …, 1997 - Elsevier
Binary membranes composed of dimyristoylphosphatidylcholine (DMPC) and natural
ceramide (up to a mole fraction X cer =0.25) were investigated by measuring the excimer:monomer …

Stimulation of Different Subtypes of Angiotensin II Receptors, AT1 and AT2 Receptors, Regulates STAT Activation by Negative Crosstalk

…, M Akishita, K Tamura, L Daviet, JYA Lehtonen… - Circulation …, 1999 - Am Heart Assoc
Angiotensin II type 2 (AT 2 ) receptor exerts an inhibitory action on cell growth. In the present
study, we report that the stimulation of AT 2 receptor in AT 2 receptor cDNA–transfected rat …

Systematic relationships of hymenolepidid cestodes of rodents and shrews inferred from sequences of 28S ribosomal RNA

…, J Laakkonen, J Niemimaa, JT Lehtonen… - Zoologica …, 2010 - Wiley Online Library
… Hardman, Jukka Niemimaa and Heikki Henttonen, Vantaa Research Unit, Finnish Forest
Research Institute, PO Box 18, FI-01301 Vantaa, Finland. E-mails: [email protected], [email …

AT2 Receptor and Vascular Smooth Muscle Cell Differentiation in Vascular Development

…, M Ito, K Tamura, L Daviet, JYA Lehtonen… - …, 1999 - Am Heart Assoc
The angiotensin II type 2 (AT 2 ) receptor is transiently expressed at late gestation in the
fetal vasculature, but its expression rapidly declines after birth. We have previously …

[HTML][HTML] Expression of the AT2 receptor developmentally programs extracellular signal-regulated kinase activity and influences fetal vascular growth

M Akishita, M Ito, JYA Lehtonen… - The Journal of …, 1999 - Am Soc Clin Investig
Angiotensin II type 2 (AT2) receptor is abundantly expressed in vascular smooth muscle cells
(VSMC) of the fetal vasculature during late gestation (embryonic day 15–20), during which …

p100 increases AT1R expression through interaction with AT1R 3′-UTR

…, KK Kontula, JYA Lehtonen - Nucleic acids …, 2008 - academic.oup.com
p100 protein (SND1, Tudor-SN) is a multifunctional protein that functions as a co-activator
for several transcription factors, has a role in mRNA processing and participates in RNAi-…