User profiles for Joshua P. Barrios

Joshua Barrios

University of California San Francisco
Verified email at ucsf.edu
Cited by 376

[PDF][PDF] Hypothalamic dopamine neurons control sensorimotor behavior by modulating brainstem premotor nuclei in zebrafish

JP Barrios, WC Wang, R England, E Reifenberg… - Current Biology, 2020 - cell.com
Dopamine (DA)-producing neurons are critically involved in the production of motor behaviors
in multiple circuits that are conserved from basal vertebrates to mammals. Although there …

[PDF][PDF] Motor behavior mediated by continuously generated dopaminergic neurons in the zebrafish hypothalamus recovers after cell ablation

AD McPherson, JP Barrios, SJ Luks-Morgan… - Current Biology, 2016 - cell.com
Postembryonic neurogenesis has been observed in several regions of the vertebrate brain,
including the dentate gyrus and rostral migratory stream in mammals, and is required for …

Zebrafish oxytocin neurons drive nocifensive behavior via brainstem premotor targets

…, AMB Lacoste, E Glushenkova, JP Barrios… - Nature …, 2019 - nature.com
Animals have evolved specialized neural circuits to defend themselves from pain- and injury-causing
stimuli. Using a combination of optical, behavioral and genetic approaches in the …

[PDF][PDF] Advancing cardiovascular medicine with machine learning: Progress, potential, and perspective

JP Barrios, GH Tison - Cell Reports Medicine, 2022 - cell.com
Recent advances in machine learning (ML) have made it possible to analyze high-dimensional
and complex data—such as free text, images, waveforms, videos, and sound—in an …

Automated assessment of cardiac systolic function from coronary angiograms with video-based artificial intelligence algorithms

R Avram, JP Barrios, S Abreau, CY Goh… - JAMA …, 2023 - jamanetwork.com
… b The P values for interaction were calculated using 2-sided Wald tests between the
video-based DNN … Drs Avram and Barrios and Mr Abreau contributed equally to this work. …

[HTML][HTML] Transgenic FingRs for live mapping of synaptic dynamics in genetically-defined neurons

JH Son, MD Keefe, TJ Stevenson, JP Barrios… - Scientific reports, 2016 - nature.com
Tools for genetically-determined visualization of synaptic circuits and interactions are
necessary to build connectomics of the vertebrate brain and to screen synaptic properties in …

Establishment of the miniature fish species Danionella translucida as a genetically and optically tractable neuroscience model

A Penalva, J Bedke, ESB Cook, JP Barrios… - biorxiv, 2018 - biorxiv.org
The rapid adoption of the larval zebrafish as a systems neuroscience model has been driven
largely by its small size and optical transparency, which enable the use of imaging and …

Regenerated interneurons integrate into locomotor circuitry following spinal cord injury

D Vasudevan, YC Liu, JP Barrios, MK Wheeler… - Experimental …, 2021 - Elsevier
Whereas humans and other adult mammals lack the ability to regain locomotor function after
spinal cord injury, zebrafish are able to recover swimming behavior even after complete …

Patient-Level Artificial Intelligence–Enhanced Electrocardiography in Hypertrophic Cardiomyopathy: Longitudinal Treatment and Clinical Biomarker Correlations

…, S Abreau, ZI Attia, JP Barrios, TA Dewland, P Agarwal… - JACC: Advances, 2023 - jacc.org
Background Artificial intelligence (AI) applied to 12-lead electrocardiographs (ECGs) can
detect hypertrophic cardiomyopathy (HCM). Objectives The purpose of this study was to …

[HTML][HTML] Deep learning augmented ECG analysis to identify biomarker-defined myocardial injury

GR Chaudhari, JJ Mayfield, JP Barrios, S Abreau… - Scientific reports, 2023 - nature.com
Chest pain is a common clinical complaint for which myocardial injury is the primary
concern and is associated with significant morbidity and mortality. To aid providers’ decision-making…