[HTML][HTML] Targeted ablation of plasma membrane Ca2+-ATPase (PMCA) 1 and 4 indicates a major housekeeping function for PMCA1 and a critical role in …

…, GJ Pyne, RL Sutliff, KT O'Connor, JC Neumann… - Journal of Biological …, 2004 - ASBMB
The relative importance of plasma membrane Ca 2+ -ATPase (PMCA) 1 and PMCA4 was
assessed in mice carrying null mutations in their genes (Atp2b1 and Atp2b4). Loss of both …

[HTML][HTML] The α2 isoform of Na, K-ATPase mediates ouabain-induced cardiac inotropy in mice

…, JN Lorenz, JEJ Schultz, IL Grupp, JC Neumann… - Journal of Biological …, 2003 - ASBMB
Inhibition of Na,K-ATPase activity by cardiac glycosides is believed to be the major
mechanism by which this class of drugs increases heart contractility. However, direct evidence …

Renal function in NHE3-deficient mice with transgenic rescue of small intestinal absorptive defect

…, PJ Schultheis, JC Neumann… - American Journal …, 2003 - journals.physiology.org
The degree to which loss of the NHE3 Na + /H + exchanger in the kidney contributes to impaired
Na + -fluid volume homeostasis in NHE3-deficient (Nhe3 −/− ) mice is unclear because …

Knockout of the Na,K-ATPase α2-isoform in the cardiovascular system does not alter basal blood pressure but prevents ACTH-induced hypertension

…, VM Lasko, ML Nieman, JC Neumann… - American Journal …, 2011 - journals.physiology.org
The α 2 -isoform of Na,K-ATPase (α 2 ) is thought to play a role in blood pressure regulation,
but the specific cell type(s) involved have not been identified. Therefore, it is important to …

Interneuron dysfunction in a new mouse model of scn1a gefs+

A Das, B Zhu, Y Xie, L Zeng, AT Pham, JC Neumann… - ENeuro, 2021 - eneuro.org
Advances in genome sequencing have identified over 1300 mutations in the SCN1A sodium
channel gene that result in genetic epilepsies. However, it still remains unclear how most …

The presence of both negative and positive elements in the 5′-flanking sequence of the rat Na, K-ATPase α3 subunit gene are required for brain expression in …

BG Pathak, JC Neumann, ML Croyle… - Nucleic acids …, 1994 - academic.oup.com
The Na, K-ATPase is an integral plasma membrane protein consisting of α and β subunits,
each of which has discrete isoforms expressed in a tissue-specific manner. Of the three …

Identification of maternally regulated fetal gene networks in the placenta with a novel embryo transfer system in mice

…, MA Sartor, KT O'Connor, JC Neumann… - Physiological …, 2011 - journals.physiology.org
The mechanisms for provisioning maternal resources to offspring in placental mammals involve
complex interactions between maternally regulated and fetally regulated gene networks …

SCN1A GEFS1

A Das, B Zhu, Y Xie, L Zeng, AT Pham, JC Neumann… - 2021 - eneuro.org
Advances in genome sequencing have identified over 1300 mutations in the SCN1A sodium
channel gene that result in genetic epilepsies. However, it still remains unclear how most …

Interneuron dysfunction in a new knock-in mouse model of SCN1A GEFS+

A Das, B Zhu, Y Xie, L Zeng, AT Pham, JC Neumann… - bioRxiv, 2019 - biorxiv.org
Advances in genome sequencing have identified over 1300 mutations in the SCN1A sodium
channel gene that result in genetic epilepsies. However, how individual mutations within …

[PDF][PDF] Identification of maternally regulated fetal gene

…, M Medvedovic, AG Menon, JC Neumann… - Physiol …, 2011 - researchgate.net
MATERIALS AND METHODS Embryo transfer. All experimental procedures involving the
use of live mice were approved by the Institutional Animal Care and Use Committee review …