User profiles for Jennifer J. Tuscher

Jennifer Tuscher

University of Alabama at Birmingham
Verified email at uab.edu
Cited by 2042

[HTML][HTML] Major histocompatibility complex genotyping with massively parallel pyrosequencing

…, BN Bimber, CE O'leary, SM Lank, JJ Tuscher… - Nature medicine, 2009 - nature.com
Major histocompatibility complex (MHC) genetics dictate adaptive cellular immune responses,
making robust MHC genotyping methods essential for studies of infectious disease, …

Sex steroid hormones matter for learning and memory: estrogenic regulation of hippocampal function in male and female rodents

KM Frick, J Kim, JJ Tuscher, AM Fortress - Learning & Memory, 2015 - learnmem.cshlp.org
Ample evidence has demonstrated that sex steroid hormones, such as the potent estrogen
17β-estradiol (E 2 ), affect hippocampal morphology, plasticity, and memory in male and …

Estradiol-mediated spine changes in the dorsal hippocampus and medial prefrontal cortex of ovariectomized female mice depend on ERK and mTOR activation in the …

JJ Tuscher, V Luine, M Frankfurt… - Journal of …, 2016 - Soc Neuroscience
Dendritic spine plasticity underlies the formation and maintenance of memories. Both natural
fluctuations and systemic administration of 17β-estradiol (E 2 ) alter spine density in the …

Regulation of object recognition and object placement by ovarian sex steroid hormones

JJ Tuscher, AM Fortress, J Kim, KM Frick - Behavioural brain research, 2015 - Elsevier
The ovarian hormones 17β-estradiol (E 2 ) and progesterone (P 4 ) are potent modulators of
hippocampal memory formation. Both hormones have been demonstrated to enhance …

A dopamine-induced gene expression signature regulates neuronal function and cocaine response

KE Savell, JJ Tuscher, ME Zipperly, CG Duke… - Science …, 2020 - science.org
Drugs of abuse elevate dopamine levels in the nucleus accumbens (NAc) and alter transcriptional
programs believed to promote long-lasting synaptic and behavioral adaptations. Here…

Inhibition of local estrogen synthesis in the hippocampus impairs hippocampal memory consolidation in ovariectomized female mice

JJ Tuscher, JS Szinte, JR Starrett, AA Krentzel… - Hormones and …, 2016 - Elsevier
The potent estrogen 17β-Estradiol (E 2 ) plays a critical role in mediating hippocampal function,
yet the precise mechanisms through which E 2 enhances hippocampal memory remain …

Canonical Wnt signaling is necessary for object recognition memory consolidation

AM Fortress, SL Schram, JJ Tuscher… - Journal of …, 2013 - Soc Neuroscience
Wnt signaling has emerged as a potent regulator of hippocampal synaptic function, although
no evidence yet supports a critical role for Wnt signaling in hippocampal memory. Here, we …

The genome of the vervet (Chlorocebus aethiops sabaeus)

…, TR Turner, RW Wiseman, JJ Tuscher… - Genome …, 2015 - genome.cshlp.org
We describe a genome reference of the African green monkey or vervet (Chlorocebus
aethiops). This member of the Old World monkey (OWM) superfamily is uniquely valuable for …

[PDF][PDF] An atlas of transcriptionally defined cell populations in the rat ventral tegmental area

RA Phillips, JJ Tuscher, SL Black, E Andraka… - Cell reports, 2022 - cell.com
The ventral tegmental area (VTA) is a complex brain region that is essential for reward function
and frequently implicated in neuropsychiatric disease. While decades of research on VTA …

MHC heterozygote advantage in simian immunodeficiency virus–infected Mauritian cynomolgus macaques

…, BJ Burwitz, BN Bimber, SM Lank, JJ Tuscher… - Science translational …, 2010 - science.org
The importance of a broad CD8 T lymphocyte (CD8-TL) immune response to HIV is unknown.
Ex vivo measurements of immunological activity directed at a limited number of defined …