Cardiomyocyte proliferation and progenitor cell recruitment underlie therapeutic regeneration after myocardial infarction in the adult mouse heart

K Malliaras, Y Zhang, J Seinfeld, G Galang… - EMBO molecular …, 2013 - embopress.org
Cardiosphere‐derived cells (CDCs) have been shown to regenerate infarcted myocardium
in patients after myocardial infarction (MI). However, whether the cells of the newly formed …

[PDF][PDF] Defects in the CAPN1 gene result in alterations in cerebellar development and cerebellar ataxia in mice and humans

…, M Hammer, Y Liu, KH Lee, V Pinto, J Seinfeld… - Cell reports, 2016 - cell.com
A CAPN1 missense mutation in Parson Russell Terrier dogs is associated with spinocerebellar
ataxia. We now report that homozygous or heterozygous CAPN1-null mutations in …

[PDF][PDF] Neuromedin s-producing neurons act as essential pacemakers in the suprachiasmatic nucleus to couple clock neurons and dictate circadian rhythms

…, M Izumo, Y Ikeda, T Motoike, S Dixon, JE Seinfeld… - Neuron, 2015 - cell.com
Circadian behavior in mammals is orchestrated by neurons within the suprachiasmatic nucleus
(SCN), yet the neuronal population necessary for the generation of timekeeping remains …

Validation of contrast-enhanced magnetic resonance imaging to monitor regenerative efficacy after cell therapy in a porcine model of convalescent myocardial …

K Malliaras, RR Smith, H Kanazawa, K Yee, J Seinfeld… - Circulation, 2013 - Am Heart Assoc
Background— Magnetic resonance imaging (MRI) in the CArdiosphere-Derived aUtologous
stem CElls to reverse ventricUlar dySfunction (CADUCEUS) trial revealed that cardiosphere-…

Cellular postconditioning: allogeneic cardiosphere-derived cells reduce infarct size and attenuate microvascular obstruction when administered after reperfusion in …

…, G De Couto, RR Smith, M Kreke, J Seinfeld… - Circulation: Heart …, 2015 - Am Heart Assoc
Background— Intracoronary delivery of cardiosphere-derived cells (CDCs) has been demonstrated
to be safe and effective in porcine and human chronic myocardial infarction. However…

Stimulation of endogenous cardioblasts by exogenous cell therapy after myocardial infarction

…, W Liu, B Sun, RC Middleton, J Seinfeld… - EMBO molecular …, 2014 - embopress.org
Controversy surrounds the identity, origin, and physiologic role of endogenous cardiomyocyte
progenitors in adult mammals. Using an inducible genetic labeling approach to identify …

[HTML][HTML] Calpain-1 deletion impairs mGluR-dependent LTD and fear memory extinction

G Zhu, V Briz, J Seinfeld, Y Liu, X Bi, M Baudry - Scientific reports, 2017 - nature.com
Recent studies indicate that calpain-1 is required for the induction of long-term potentiation (LTP)
elicited by theta-burst stimulation in field CA1 of hippocampus. Here we determined the …

[HTML][HTML] Allogeneic cardiospheres delivered via percutaneous transendocardial injection increase viable myocardium, decrease scar size, and attenuate cardiac …

…, JF Dawkins, S Chowdhury, DT Duong, J Seinfeld… - PloS one, 2014 - journals.plos.org
Background Epicardial injection of heart-derived cell products is safe and effective post-myocardial
infarction (MI), but clinically-translatable transendocardial injection has never been …

[BOOK][B] The bad object: Handling the negative therapeutic reaction in psychotherapy.

J Seinfeld - 1990 - psycnet.apa.org
This book is about the psychodynamics and treatment of the negative therapeutic reaction—the
patient's inability to tolerate progress in treatment. With abundant clinical material, …

Spirituality in social work practice

J Seinfeld - Clinical Social Work Journal, 2012 - Springer
This article traces the origins of spirituality in clinical social work and psychotherapy from the
nineteenth century to contemporary practice. Cases involving bereavement, terminal illness…