A prospective, multicenter phase I trial was undertaken by the North American Clinical Trials
Network (NACTN) to investigate the pharmacokinetics and safety of, as well as obtain pilot …

The rationale for implantation of autologous human Schwann cells (SCs) in persons with
subacute spinal cord injury (SCI) is based on evidence that transplanted SCs are …

Spinal cord injury is a severely disabling neurological condition leading to impaired mobility,
pain, and autonomic dysfunction. Most often, a single traumatic event, such as a traffic or …

Large animal and primate models of spinal cord injury (SCI) are being increasingly utilized
for the testing of novel therapies. While these represent intermediary animal species between …

To improve clinicians' ability to predict outcome after spinal cord injury (SCI) and to help
classify patients within clinical trials, we have created a novel prediction model relating acute …

Object The aim of this multicenter, prospective study was to determine the spectrum, incidence,
and severity of complications during the initial hospitalization of patients with spinal cord …

Study Design Literature Review (Narrative) Objective To propose a new framework, to
support the investigation and understanding of the pathobiology of DCM, AO Spine RECODE-…

A phase 1 open-label, non-randomized clinical trial was conducted to determine feasibility
and safety of autologous human Schwann cell (ahSC) transplantation accompanied by …

The past three decades have seen an explosion of research interest in spinal cord injury (SCI)
and the development of hundreds of potential therapies that have demonstrated some …

The histological assessment of spinal cord tissue in three dimensions has previously been
very time consuming and prone to errors of interpretation. Advances in tissue clearing have …