mTOR controls mitochondrial oxidative function through a YY1–PGC-1α transcriptional complex
Transcriptional complexes that contain peroxisome-proliferator-activated receptor coactivator
(PGC)-1α control mitochondrial oxidative function to maintain energy homeostasis in …
(PGC)-1α control mitochondrial oxidative function to maintain energy homeostasis in …
Pancreatic stenting prevents pancreatitis after biliary sphincterotomy in patients with sphincter of Oddi dysfunction
PR Tarnasky, YY Palesch, JT Cunningham… - Gastroenterology, 1998 - Elsevier
Background & Aims: Patients with sphincter of Oddi dysfunction are at high risk of developing
pancreatitis after endoscopic biliary sphincterotomy. Impaired pancreatic drainage caused …
pancreatitis after endoscopic biliary sphincterotomy. Impaired pancreatic drainage caused …
[HTML][HTML] ER stress–mediated autophagy promotes Myc-dependent transformation and tumor growth
LS Hart, JT Cunningham, T Datta, S Dey… - The Journal of …, 2012 - Am Soc Clin Investig
The proto-oncogene c-Myc paradoxically activates both proliferation and apoptosis. In the
pathogenic state, c-Myc–induced apoptosis is bypassed via a critical, yet poorly understood …
pathogenic state, c-Myc–induced apoptosis is bypassed via a critical, yet poorly understood …
Prospective assessment of the ability of endoscopic ultrasound to diagnose, exclude, or establish the severity of chronic pancreatitis found by endoscopic retrograde …
…, L Aabakken, PR Tarnasky, JT Cunningham… - Gastrointestinal …, 1998 - Elsevier
Background: Our aim was to verify endoscopic ultrasound (EUS) accuracy to diagnose, rule
out, and establish the severity of chronic pancreatitis found by endoscopic retrograde …
out, and establish the severity of chronic pancreatitis found by endoscopic retrograde …
[HTML][HTML] Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer
JT Cunningham, MV Moreno, A Lodi, SM Ronen… - Cell, 2014 - cell.com
Cancer cells must integrate multiple biosynthetic demands to drive indefinite proliferation.
How these key cellular processes, such as metabolism and protein synthesis, crosstalk to fuel …
How these key cellular processes, such as metabolism and protein synthesis, crosstalk to fuel …
Long-term outcomes for patients with post–liver transplant anastomotic biliary strictures treated by endoscopic stent placement
…, HE Mulcahy, IR Willner, JT Cunningham… - Gastrointestinal …, 2003 - Elsevier
BACKGROUND:: Biliary stricture is one of the most common complications of liver transplantation.
A number of treatment options are available, but a standard approach has not been …
A number of treatment options are available, but a standard approach has not been …
Large-diameter biliary orifice balloon dilation to aid in endoscopic bile duct stone removal: a multicenter series
…, DA Howell, DE Wakelin, JT Cunningham… - Gastrointestinal …, 2008 - Elsevier
BACKGROUND: The utility and safety of endoscopic biliary orifice balloon dilation (EBD) for
bile duct stone removal (with use of large-diameter balloons) after biliary endoscopic …
bile duct stone removal (with use of large-diameter balloons) after biliary endoscopic …
Comparative costs of metal versus plastic biliary stent strategies for malignant obstructive jaundice by decision analysis
KG Yeoh, MJ Zimmerman, JT Cunningham… - Gastrointestinal …, 1999 - Elsevier
Background: For palliation of patients with malignant obstructive jaundice, expansile metal
stents provide longer patency than plastic stents but are more expensive. The optimal cost-…
stents provide longer patency than plastic stents but are more expensive. The optimal cost-…
Translation control of the immune checkpoint in cancer and its therapeutic targeting
…, S Asthana, M Barna, KR Webster, JT Cunningham… - Nature medicine, 2019 - nature.com
Cancer cells develop mechanisms to escape immunosurveillance, among which
modulating the expression of immune suppressive messenger RNAs is most well-documented. …
modulating the expression of immune suppressive messenger RNAs is most well-documented. …
Evaluation of unexplained acute and acute recurrent pancreatitis using endoscopic retrograde cholangiopancreatography, sphincter of Oddi manometry and …
…, L Aabakken, BJ Hoffman, JT Cunningham… - …, 2002 - thieme-connect.com
Results: ERCP was successful in 88/89 patients (99%). Manometry was successful in 63/67
patients (94%), and 56 patients underwent EUS. Findings were categorized into five distinct …
patients (94%), and 56 patients underwent EUS. Findings were categorized into five distinct …