The capacity to use tools is a fundamental evolutionary achievement. Its essence stands in
the capacity to transfer a proximal goal (grasp a tool) to a distal goal (eg, grasp food). Where …

Mirror neurons are a distinct class of neurons that discharge both during the execution of a
motor act and during observation of the same or similar motor act performed by another …

Activation of nicotinic acetylcholine receptors (nAChRs) by systemic nicotine enhances
sensory-cognitive function and sensory-evoked cortical responses. Although nAChRs mediate …

Although it has been known for decades that the drug nicotine can improve cognitive function,
the nature of its effects and the underlying mechanisms are not well understood. Nicotine …

Nicotine enhances sensory and cognitive processing via actions at nicotinic acetylcholine
receptors (nAChRs), yet the precise circuit- and systems-level mechanisms remain unclear. In …

Auditory-cued behavioral training can alter neural circuits in primary auditory cortex (A1), but
the mechanisms and consequences of experience-dependent cortical plasticity are not fully …

The GABAergic agonist muscimol is used to inactivate brain regions in order to reveal
afferent inputs in isolation. However, muscimol's use in primary auditory cortex (A1) has been …

Primary auditory cortex (A1) exhibits a tonotopic representation of characteristic frequency (CF).
The receptive field properties of A1 neurons emerge from a combination of thalamic …

Nicotinic acetylcholine α4β2 ∗ receptors (nAChRs) are implicated in various neurodegenerative
diseases and smoking addiction. Imaging of brain high-affinity α4β2 ∗ nAChRs at the …

Systemic nicotine enhances neural processing in primary auditory cortex (A1) as determined
using tone-evoked, current-source density (CSD) measurements. For example, nicotine …